CNNM2_MOUSE Q3TWN3
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UniProt:Q3TWN3
Recommended name：Metal transporter CNNM2
EC number：
Alternative names：(Ancient conserved domain-containing protein 2) (mACDP2) (Cyclin-M2)
Cleaved into：
GeneID：94219
Gene names (primary )：Cnnm2
Gene names (synonym )：Acdp2
Gene names (ORF )：
Length：875
Mass：96704
Sequence：MIGCGACEPEVKMAGGQAAAALPTWKMAARRSLSARGRGVLQAAAGRLLPLLLLSCCWGAGGCTAAGENEETVIIGLRLEDTNDVSFMEGGALRVSERTRVKLRVYGQNINNETWSRIAFTEHERRRHTPSERGLGGPAPPEPDSGPQRCGIRTSDIIILPHIILNRRTSGIIEIEIKPLRKMEKSKSYYLCTSLSTPALGAGGSGSASGTVGGKGGAGVAGLPPPPWAETTWIYHDGEDTKMIVGEEKKFLLPFWLQVIFISLLLCLSGMFSGLNLGLMALDPMELRIVQNCGTEKEKNYAKRIEPVRRQGNYLLCSLLLGNVLVNTTLTILLDDIAGSGLVAVVVSTIGIVIFGEIVPQAICSRHGLAVGANTIFLTKFFMMMTFPASYPVSKLLDCVLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRTKTVEDVMTPLRDCFMITGEAILDFNTMSEIMESGYTRIPVFEGERSNIVDLLFVKDLAFVDPDDCTPLKTITKFYNHPLHFVFNDTKLDAMLEEFKKGKSHLAIVQRVNNEGEGDPFYEVLGIVTLEDVIEEIIKSEILDETDLYTDNRTKKKVAHRERKQDFSAFKQTDSEMKVKISPQLLLAMHRFLATEVEAFSPSQMSEKILLRLLKHPNVIQELKYDEKNKKAPECYLYQRNKPVDYFVLILQGKVEVEAGKEGMKFEASAFSYYGVMALTASPVPLSLSRTFVVSRTEVLAAGSPGENKSPPRPCGLNHSDSLSRSDRIDAMTPTLGSSNNQLSSSFLQVYIPDYSVRALSDLQFVKISRQQYQNALMASRMDKTPQSSDSENTKIELTLTELHDGLPDETANLLNEQNCVSHNKANHSLHSEGAI
Tissue specificity：Widely expressed, with highest levels in kidney, lung, spleen and testis. In the kidney, predominantly expressed in the distal convoluted tubule and, at lower levels, in the connecting tubule (at protein level). {ECO:0000269|PubMed:14723793, ECO:0000269|PubMed:15899945, ECO:0000269|PubMed:22399287}.
Induction：By low Mg(2+) concentration. {ECO:0000269|PubMed:15899945}.
Developmental stage：
Protein families：ACDP family