IL27A_MOUSE Q8K3I6
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UniProt:Q8K3I6
Recommended name：Interleukin-27 subunit alpha
EC number：
Alternative names：(IL-27 subunit alpha) (IL-27-A) (IL27-A) (p28)
Cleaved into：
GeneID：246779
Gene names (primary )：Il27
Gene names (synonym )：Il27a
Gene names (ORF )：
Length：234
Mass：26542
Sequence：MGQVTGDLGWRLSLLLLPLLLVQAGSWGFPTDPLSLQELRREFTVSLYLARKLLSEVQGYVHSFAESRLPGVNLDLLPLGYHLPNVSLTFQAWHHLSDSERLCFLATTLRPFPAMLGGLGTQGTWTSSEREQLWAMRLDLRDLHRHLRFQVLAAGFKCSKEEEDKEEEEEEEEEEKKLPLGALGGPNQVSSQVSWPQLLYTYQLLHSLELVLSRAVRDLLLLSLPRRPGSAWDS
Tissue specificity：Expressed in macrophages and dendritic cells. {ECO:0000269|PubMed:12121660}.
Induction：By LPS and Interferon gamma in primary astrocytes and microglia. Induced by Toll-like receptor ligand in dendritic cells. Inhibited by PPAR-alpha agonist such as fenofibrate and produced by TNF-alpha in microglia. {ECO:0000269|PubMed:15804443, ECO:0000269|PubMed:16906166, ECO:0000269|PubMed:17548596, ECO:0000269|PubMed:17709543, ECO:0000269|PubMed:17727629}.
Developmental stage：
Protein families：IL-6 superfamily