RIPP2_MOUSE Q2WG76
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UniProt:Q2WG76
Recommended name:Protein ripply2
EC number:
Alternative names:
Cleaved into:
GeneID:382089
Gene names (primary ):Ripply2
Gene names (synonym ):
Gene names (ORF ):
Length:128
Mass:14305
Sequence:MDTTESAESAHNPARPPSRSRCPPSAQPGSEGFWRPWVRTPGEKEKRTGPRAAEALPSGPGMAEASGKLLQYQHPVRLFWPKSKCYDYLYQEAETLLKNFPIQATISFYEDSDSEDEIEGLACENQSN
Tissue specificity:Expressed in the embryonic anterior presomitic mesoderm. First expressed in S-I at E8.5, where expression is maintained until E13.5, with an additional stripe of expression sometimes seen in the rostral part of S0 and S-I. {ECO:0000269|PubMed:16326386, ECO:0000269|PubMed:17531978}.
Induction:By MESP2, and acts in a negative feedback loop with MESP2, functioning negatively toward MESP2 to regulate NOTCH signaling in the anterior presomitic mesoderm. {ECO:0000269|PubMed:17360776}.
Developmental stage:
Protein families:Ripply family