ALOX8_MOUSE O35936
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UniProt:O35936
Recommended name：Polyunsaturated fatty acid lipoxygenase ALOX8
EC number：EC 1.13.11.-
Alternative names：(15-lipoxygenase 2) (15-LOX-2) (Arachidonate 15-lipoxygenase B) (15-LOX-B) (Arachidonate 8S-lipoxygenase) (8-LOX) (8S-LOX) (Linoleate 9S-lipoxygenase ALOX8) (EC 1.13.11.58)
Cleaved into：
GeneID：11688
Gene names (primary )：Alox8
Gene names (synonym )：Alox15b
Gene names (ORF )：
Length：677
Mass：76230
Sequence：MAKCRVRVSTGEACGAGTWDKVSVSIVGTHGESPLVPLDHLGKEFSAGAEEDFEVTLPQDVGTVLMLRVHKAPPEVSLPLMSFRSDAWFCRWFELEWLPGAALHFPCYQWLEGAGELVLREGAAKVSWQDHHPTLQDQRQKELESRQKMYSWKTYIEGWPRCLDHETVKDLDLNIKYSAMKNAKLFFKAHSAYTELKVKGLLDRTGLWRSLREMRRLFNFRKTPAAEYVFAHWQEDAFFASQFLNGINPVLIRRCHSLPNNFPVTDEMVAPVLGPGTSLQAELEKGSLFLVDHGILSGVHTNILNGKPQFSAAPMTLLHQSSGSGPLLPIAIQLKQTPGPDNPIFLPSDDTWDWLLAKTWVRNSEFYIHEAVTHLLHAHLIPEVFALATLRQLPRCHPLFKLLIPHIRYTLHINTLARELLVAPGKLIDKSTGLGTGGFSDLIKRNMEQLNYSVLCLPEDIRARGVEDIPGYYYRDDGMQIWGAIKSFVSEIVSIYYPSDTSVQDDQELQAWVREIFSEGFLGRESSGMPSLLDTREALVQYITMVIFTCSAKHAAVSSGQFDSCVWMPNLPPTMQLPPPTSKGQARPESFIATLPAVNSSSYHIIALWLLSAEPGDQRPLGHYPDEHFTEDAPRRSVAAFQRKLIQISKGIRERNRGLALPYTYLDPPLIENSVSI
Tissue specificity：Expressed in epidermis and brain (PubMed:9305900, PubMed:9518531). No expression found in heart, spleen, liver, skeletal muscle, kidney or testis. {ECO:0000269|PubMed:9305900, ECO:0000269|PubMed:9518531}.
Induction：By phorbol ester. {ECO:0000269|PubMed:9305900}.
Developmental stage：
Protein families：Lipoxygenase family