ACMSD_MOUSE Q8R519
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UniProt:Q8R519
Recommended name:2-amino-3-carboxymuconate-6-semialdehyde decarboxylase
EC number:EC 4.1.1.45
Alternative names:(Picolinate carboxylase)
Cleaved into:
GeneID:266645
Gene names (primary ):Acmsd
Gene names (synonym ):
Gene names (ORF ):
Length:336
Mass:38027
Sequence:MKIDIHTHILPKEWPDLEKRFGYGGWVQLQQQGKGEAKMIKDGKLFRVIQQNCWDPEVRIREMNQKGVTVQALSTVPVMFSYWAKPKDTLELCQFLNNDLAATVARYPRRFVGLGTLPMQAPELAVEEMERCVKALGFPGIQIGSHINTWDLNDPELFPIYAAAERLNCSLFVHPWDMQMDGRMAKYWLPWLVGMPSETTMAICSMIMGGVFEKFPKLKVCFAHGGGAFPFTIGRIAHGFNMRPDLCAQDNPSDPRKYLGSFYTDSLVHDPLSLKLLTDVIGKDKVMLGTDYPFPLGEQEPGKLIESMAEFDEETKDKLTAGNALAFLGLERKLFE
Tissue specificity:Highest expression in kidney with lower levels in liver and brain. {ECO:0000269|PubMed:12140278}.
Induction:By streptozocin-induced diabetes. Repressed by low protein diet. {ECO:0000269|PubMed:12140278}.
Developmental stage:
Protein families:Metallo-dependent hydrolases superfamily, ACMSD family