FOXP3_MOUSE   Q99JB6


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UniProt:Q99JB6

Recommended name:Forkhead box protein P3

EC number:

Alternative names:(Scurfin)

Cleaved into:Forkhead box protein P3, C-terminally processed; Forkhead box protein P3 41 kDa form

GeneID:20371

Gene names  (primary ):Foxp3

Gene names  (synonym ):

Gene names  (ORF ):

Length:429

Mass:47346

Sequence:MPNPRPAKPMAPSLALGPSPGVLPSWKTAPKGSELLGTRGSGGPFQGRDLRSGAHTSSSLNPLPPSQLQLPTVPLVMVAPSGARLGPSPHLQALLQDRPHFMHQLSTVDAHAQTPVLQVRPLDNPAMISLPPPSAATGVFSLKARPGLPPGINVASLEWVSREPALLCTFPRSGTPRKDSNLLAAPQGSYPLLANGVCKWPGCEKVFEEPEEFLKHCQADHLLDEKGKAQCLLQREVVQSLEQQLELEKEKLGAMQAHLAGKMALAKAPSVASMDKSSCCIVATSTQGSVLPAWSAPREAPDGGLFAVRRHLWGSHGNSSFPEFFHNMDYFKYHNMRPPFTYATLIRWAILEAPERQRTLNEIYHWFTRMFAYFRNHPATWKNAIRHNLSLHKCFVRVESEKGAVWTVDEFEFRKKRSQRPNKCSNPCP

Tissue specificity:High level of expression in thymus and spleen.

Induction:By TGFB1 in T-cells. Down-regulated in regulatory T-cells (Treg) during inflammation. {ECO:0000269|PubMed:18368049, ECO:0000269|PubMed:23973223}.

Developmental stage:

Protein families:


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