SMAD6_MOUSE O35182
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UniProt:O35182
Recommended name:Mothers against decapentaplegic homolog 6
EC number:
Alternative names:(MAD homolog 6) (Mothers against DPP homolog 6) (Mad homolog 7) (SMAD family member 6) (SMAD 6) (Smad6)
Cleaved into:
GeneID:17130
Gene names (primary ):Smad6
Gene names (synonym ):Madh6 Madh7 Msmad6
Gene names (ORF ):
Length:495
Mass:53714
Sequence:MFRSKRSGLVRRLWRSRVVPDREEGSGGGGGVDEDGSLGSRAEPAPRAREGGGCSRSEVRSVAPRRPRDAVGPRGAAIAGRRRRTGGLPRPVSESGAGAGGSPLDVAEPGGPGWLPESDCETVTCCLFSERDAAGAPRDSGDPQARQSPEPEEGGGPRSREARSRLLLLEQELKTVTYSLLKRLKERSLDTLLEAVESRGGVPGGCVLVPRADLRLGGQPAPPQLLLGRLFRWPDLQHAVELKPLCGCHSFTAAADGPTVCCNPYHFSRLCGPESPPPPYSRLSPPDQYKPLDLSDSTLSYTETEATNSLITAPGEFSDASMSPDATKPSHWCSVAYWEHRTRVGRLYAVYDQAVSIFYDLPQGSGFCLGQLNLEQRSESVRRTRSKIGFGILLSKEPDGVWAYNRGEHPIFVNSPTLDAPGGRALVVRKVPPGYSIKVFDFERSGLLQHADAAHGPYDPHSVRISFAKGWGPCYSRQFITSCPCWLEILLNNHR
Tissue specificity:Ubiquitous in various organs, with higher levels in lung.
Induction:By TGF-beta and BMP4. {ECO:0000269|PubMed:16951688}.
Developmental stage:
Protein families:Dwarfin/SMAD family