CLC5A_MOUSE   Q9R007


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UniProt:Q9R007

Recommended name:C-type lectin domain family 5 member A

EC number:

Alternative names:(C-type lectin superfamily member 5) (Myeloid DAP12-associating lectin 1) (MDL-1)

Cleaved into:

GeneID:23845

Gene names  (primary ):Clec5a

Gene names  (synonym ):Clecsf5 Mdl1

Gene names  (ORF ):

Length:190

Mass:21696

Sequence:MNWHMIISGLIVVVIKVVGMTFFLLYFPQVFGKSNDGFVPTESYGTTSVQNVSQIFGRNDESTMPTRSYGTVCPRNWDFHQGKCFFFSFSESPWKDSMDYCATQGSTLAIVNTPEKLKYLQDIAGIENYFIGLVRQPGEKKWRWINNSVFNGNVTNQDQNFDCVTIGLTKTYDAASCEVSYRWICEMNAK

Tissue specificity:Strong expression in bone marrow cells and thioglycollate-induced neutrophils (at protein level) (PubMed:19074552). Expressed on granulocytes and monocytes from bone marrow and peripheral blood (PubMed:20212065). Expressed in macrophage cell line J-774, but not in T-cell lines, B-cell lines, or mast cell lines (PubMed:10449773). {ECO:0000269|PubMed:10449773, ECO:0000269|PubMed:19074552, ECO:0000269|PubMed:20212065}.

Induction:By TNF in bone-marrow derived macrophage colony-stimulating factor-dependent macrophages (PubMed:20212065). Up-regulated during the differentiation of myeloid cell line 32Dcl3 into neutrophils (PubMed:19074552). {ECO:0000269|PubMed:19074552, ECO:0000269|PubMed:20212065}.

Developmental stage:

Protein families:


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