MADCA_MOUSE Q61826
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UniProt:Q61826
Recommended name：Mucosal addressin cell adhesion molecule 1
EC number：
Alternative names：(MAdCAM-1) (mMAdCAM-1)
Cleaved into：
GeneID：
Gene names (primary )：Madcam1
Gene names (synonym )：
Gene names (ORF )：
Length：405
Mass：43652
Sequence：MESILALLLALALVPYQLSRGQSFQVNPPESEVAVAMGTSLQITCSMSCDEGVARVHWRGLDTSLGSVQTLPGSSILSVRGMLSDTGTPVCVGSCGSRSFQHSVKILVYAFPDQLVVSPEFLVPGQDQVVSCTAHNIWPADPNSLSFALLLGEQRLEGAQALEPEQEEEIQEAEGTPLFRMTQRWRLPSLGTPAPPALHCQVTMQLPKLVLTHRKEIPVLQSQTSPKPPNTTSAEPYILTSSSTAEAVSTGLNITTLPSAPPYPKLSPRTLSSEGPCRPKIHQDLEAGWELLCEASCGPGVTVRWTLAPGDLATYHKREAGAQAWLSVLPPGPMVEGWFQCRQDPGGEVTNLYVPGQVTPNSSSTVVLWIGSLVLGLLALVFLAYRLWKCYRPGPRPDTSSCTHL
Tissue specificity：Highly expressed on high endothelial venules (HEV) of organized intestinal lymphoid tissues like the Peyer patches and mesenteric lymph nodes, and in the lamina propria of the intestine. Some expression found in the spleen, and low levels of expression in the peripheral lymph nodes and the lactating mammary gland. No expression was detected in the liver, kidneys, lungs or in normal brain. Expressed as well in brain endothelioma cells, and mucosal tissues which are in a chronic state of inflammation, such as inflamed pancreas. {ECO:0000269|PubMed:3340147, ECO:0000269|PubMed:7693764, ECO:0000269|PubMed:8502297}.
Induction：By TNF-alpha, and chronic inflammation. {ECO:0000269|PubMed:7693764, ECO:0000269|PubMed:7724598}.
Developmental stage：
Protein families：