DP13B_MOUSE Q8K3G9
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UniProt:Q8K3G9
Recommended name：DCC-interacting protein 13-beta
EC number：
Alternative names：(Dip13-beta) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 2)
Cleaved into：
GeneID：216190
Gene names (primary )：Appl2
Gene names (synonym )：Dip13b Dip3b
Gene names (ORF )：
Length：662
Mass：73854
Sequence：MPAVDKLLLEEALQDSPQARSLLSVFEEDAGTLTDYTNQLLQAMQRVYGAQNEMCLATQQLSRQLLAYEKQNFALGKGDEEVISTLHYFSKVMDELNGLHTELAKQLADTMVLPVIQFREKDLTEVSTLKDLFGLASSEHDLSMAKYSRLPKKKENEKAKTEIVKEVAAARRKQHLSSLQYYCALNALQYRKRAAMMEPLIGFAHGQINFFKRGAEMFSKSMDGFLSSVKDMVQSIQVELEAEADKMRVSQQELLSVSESVYTPDIDVATAQINRNLIQKTGYLNLRNKTGLVTTTWERLYFFTQGGNLMCQPRGAVAGGLIQDLDNCSVMAVDCEDRRYCFQISTPSGKPGIILQAESRKEYEEWICAVNNISRQIYLTDNPEAVAIKLNQTALQAVTPITSFGKKQESSCSSQNIKNSDIEDDNIVPKATASIPETEELIAPGTPIQFDIVLPATEFLDQNRGGRRTNPFGETEDGSFPEAEDSLLQQMFIVRFLGSMAVKTDSTAEVIYEAMRQVLAARAIHNIFRMTESHLMVTSQTLRLIDPQTQVSRACFELTSVTQFAAHQENKRLVGFVIRVPESTGEESLSTYIFESNSEGEKICYAINLGKEIIEVQKDPEALARLMLSVPLTNDGKYVLLNDQADDTGGSPSENRGAESEA
Tissue specificity：Expressed in insulin-target tissues including skeletal muscle, liver, fat, and brain. Highly expressed in kidney and pancreas (PubMed:19661063). Abundantly expressed in the ventromedial hypothalamus (VMH), barely detectable in the arcuate nucleus (ARC) and paraventricular nucleus (PVN) of the hypothalamus. Also expressed in pancreatic beta-cells (PubMed:29467283). {ECO:0000269|PubMed:19661063, ECO:0000269|PubMed:29467283}.
Induction：Decreases steadily in response to lipopolysaccharide (LPS). {ECO:0000269|PubMed:25328665}.
Developmental stage：
Protein families：