HYCCI_MOUSE Q6P9N1
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UniProt:Q6P9N1
Recommended name:Hyccin
EC number:
Alternative names:(Down-regulated by CTNNB1 protein A) (Protein FAM126A)
Cleaved into:
GeneID:84652
Gene names (primary ):Fam126a
Gene names (synonym ):Drctnnb1a
Gene names (ORF ):
Length:521
Mass:57321
Sequence:MFTSEIGVVEEWLSEFKTLPETSLPNYATNLKDKSSLVTSLYKVIQEPQSELLEPVCHQLFEFYRSGEEQLLRFTLQFLPELMWCYLAVSASRDVHSSGCIEALLLGVYNLEIVDKHGHSKVLSFTIPSLSKPSVYHEPSSIGSMALTESALSQHGLSKVVYSGPHPQREMLTAQNRFEVLTFLLLCYNAALTYMPSVSLQSLCQICSRICVCGYPRQHVRKYRGVSSRIPISSGFMVQMLTGVYFAIYNGEWDLAQKALDDIIYRAQLELYPEPLLVANAIKASLPHGAMKSSKEGTRCIQVEITPTSSRISRNAVTSMSIRGHRWKRHGDTELTGQEELMDITEVDEGFYSRAASSTSQSGLSNSSHNCSNKTSVGKNQRRSGGSKAGAKERETAGESCRDHFARKQTQRAQSENLELLSLKRLTLTSSQSLPKPSSQGLAKTAATVFSKSFEQVSGAPVPRSPSPAIGCVAGADANRFSACSLQEEKLIYVSERTELAVKCQAGQQGPPSISVTLSAE
Tissue specificity:Predominantly expressed in the central nervous system, where it is found in neurons but not in myelinating cells. Lower abundance is observed in peripheral neurons, where it is detectable only at early postnatal ages (PubMed:22461884). Expressed in both oligodendrocytes and neurons (PubMed:26571211). {ECO:0000269|PubMed:22461884, ECO:0000269|PubMed:26571211}.
Induction:Down-regulated by beta-catenin. {ECO:0000269|PubMed:10910037}.
Developmental stage:
Protein families:FAM126 family