RDH11_MOUSE Q9QYF1
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UniProt:Q9QYF1
Recommended name:Retinol dehydrogenase 11
EC number:EC 1.1.1.300
Alternative names:(Androgen-regulated short-chain dehydrogenase/reductase 1) (Cell line MC/9.IL4-derived protein 1) (M42C60) (Prostate short-chain dehydrogenase/reductase 1) (Retinal reductase 1) (RalR1) (Short-chain aldehyde dehydrogenase) (SCALD)
Cleaved into:
GeneID:17252
Gene names (primary ):Rdh11
Gene names (synonym ):Arsdr1 Mdt1 Psdr1
Gene names (ORF ):
Length:316
Mass:35148
Sequence:MFGFLLLLSLPFILYLVTPKIRKMLSSGVCTSNVQLPGKVAIVTGANTGIGKETAKDLAQRGARVYLACRDVDKGELAAREIQAVTGNSQVFVRKLDLADTKSIRAFAKDFLAEEKHLHLLINNAGVMMCPYSKTADGFEMHIGVNHLGHFLLTHLLLEKLKESAPSRIVNLSSLGHHLGRIHFHNLQGEKFYSAGLAYCHSKLANILFTKELAKRLKGSGVTTYSVHPGTVHSELTRYSSIMRWLWQLFFVFIKTPQEGAQTSLYCALTEGLESLSGSHFSDCQLAWVSYQGRNEIIARRLWDVSCDLLGLPVDW
Tissue specificity:Expressed at high level in liver and testis (PubMed:12807874, PubMed:15790565, PubMed:29567832). Expressed at lower levels in smooth muscle, thymus, submaxillary gland and epididymis. In testis, expression is restricted to pachytene spermatocytes. Also expressed in four layers of the retina, including the outer segment of rods and cones (PubMed:12807874, PubMed:15790565). {ECO:0000269|PubMed:12807874, ECO:0000269|PubMed:15790565, ECO:0000269|PubMed:29567832}.
Induction:Down-regulated in liver by fasting and rose by refeeding. {ECO:0000269|PubMed:12807874, ECO:0000269|PubMed:29567832}.
Developmental stage:
Protein families:Short-chain dehydrogenases/reductases (SDR) family