RDH11_MOUSE   Q9QYF1


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UniProt:Q9QYF1

Recommended name:Retinol dehydrogenase 11

EC number:EC 1.1.1.300

Alternative names:(Androgen-regulated short-chain dehydrogenase/reductase 1) (Cell line MC/9.IL4-derived protein 1) (M42C60) (Prostate short-chain dehydrogenase/reductase 1) (Retinal reductase 1) (RalR1) (Short-chain aldehyde dehydrogenase) (SCALD)

Cleaved into:

GeneID:17252

Gene names  (primary ):Rdh11

Gene names  (synonym ):Arsdr1 Mdt1 Psdr1

Gene names  (ORF ):

Length:316

Mass:35148

Sequence:MFGFLLLLSLPFILYLVTPKIRKMLSSGVCTSNVQLPGKVAIVTGANTGIGKETAKDLAQRGARVYLACRDVDKGELAAREIQAVTGNSQVFVRKLDLADTKSIRAFAKDFLAEEKHLHLLINNAGVMMCPYSKTADGFEMHIGVNHLGHFLLTHLLLEKLKESAPSRIVNLSSLGHHLGRIHFHNLQGEKFYSAGLAYCHSKLANILFTKELAKRLKGSGVTTYSVHPGTVHSELTRYSSIMRWLWQLFFVFIKTPQEGAQTSLYCALTEGLESLSGSHFSDCQLAWVSYQGRNEIIARRLWDVSCDLLGLPVDW

Tissue specificity:Expressed at high level in liver and testis (PubMed:12807874, PubMed:15790565, PubMed:29567832). Expressed at lower levels in smooth muscle, thymus, submaxillary gland and epididymis. In testis, expression is restricted to pachytene spermatocytes. Also expressed in four layers of the retina, including the outer segment of rods and cones (PubMed:12807874, PubMed:15790565). {ECO:0000269|PubMed:12807874, ECO:0000269|PubMed:15790565, ECO:0000269|PubMed:29567832}.

Induction:Down-regulated in liver by fasting and rose by refeeding. {ECO:0000269|PubMed:12807874, ECO:0000269|PubMed:29567832}.

Developmental stage:

Protein families:Short-chain dehydrogenases/reductases (SDR) family


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