TIMD4_MOUSE Q6U7R4
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UniProt:Q6U7R4
Recommended name：T-cell immunoglobulin and mucin domain-containing protein 4
EC number：
Alternative names：(TIMD-4) (Spleen, mucin-containing, knockout of lymphotoxin protein) (SMUCKLER) (T-cell immunoglobulin mucin receptor 4) (TIM-4) (T-cell membrane protein 4)
Cleaved into：
GeneID：276891
Gene names (primary )：Timd4
Gene names (synonym )：Tim4
Gene names (ORF )：
Length：343
Mass：37548
Sequence：MSKGLLLLWLVTELWWLYLTPAASEDTIIGFLGQPVTLPCHYLSWSQSRNSMCWGKGSCPNSKCNAELLRTDGTRIISRKSTKYTLLGKVQFGEVSLTISNTNRGDSGVYCCRIEVPGWFNDVKKNVRLELRRATTTKKPTTTTRPTTTPYVTTTTPELLPTTVMTTSVLPTTTPPQTLATTAFSTAVTTCPSTTPGSFSQETTKGSAFTTESETLPASNHSQRSMMTISTDIAVLRPTGSNPGILPSTSQLTTQKTTLTTSESLQKTTKSHQINSRQTILIIACCVGFVLMVLLFLAFLLRGKVTGANCLQRHKRPDNTEDSDSVLNDMSHGRDDEDGIFTL
Tissue specificity：Predominantly expressed in lymphoid tissues, such as spleen, lymph nodes, and Peyer patches. Also expressed in fetal liver, salivary gland, and spleen stromal cells, predominantly in the marginal zone and to a lesser extent throughout the white pulp. Not expressed by bone marrow-derived cells. In spleen, expressed mostly by stromal cells in T- and B-cell areas, but not by T or B-lymphocytes. {ECO:0000269|PubMed:14768054, ECO:0000269|PubMed:17960135}.
Induction：Down-regulated in lymphotoxin deficient mice. {ECO:0000269|PubMed:14768054}.
Developmental stage：
Protein families：Immunoglobulin superfamily, TIM family