BDH2_MOUSE Q8JZV9
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UniProt:Q8JZV9
Recommended name:3-hydroxybutyrate dehydrogenase type 2
EC number:EC 1.1.1.-
Alternative names:(Dehydrogenase/reductase SDR family member 6) (R-beta-hydroxybutyrate dehydrogenase)
Cleaved into:
GeneID:69772
Gene names (primary ):Bdh2
Gene names (synonym ):Dhrs6
Gene names (ORF ):
Length:245
Mass:26753
Sequence:MGRLDGKVIVLTAAAQGIGRASALAFAREGAKVIATDINESKLQELESYRGIQTRVLDVTKKRQIDQFASEIERIDVLFNVAGFVHHGTILDCEEKDWDFSMNLNVRSMFLMIKAFLPKMLAQKSGNIINMSSVASSIKGVENRCVYSATKAAVIGLTKSVAADFIQQGIRCNCVCPGTVDTPSLQERIQARDNPKEALKTFLNRQKTGRFASAEEVALLCVYLASDESAYVTGNPVIIDGGWSL
Tissue specificity:Detected in liver, spleen and macrophages (PubMed:24863067). Widely expressed. {ECO:0000269|PubMed:20550936, ECO:0000269|PubMed:24863067}.
Induction:Down-regulated in macrophages by exposure to bacterial lipopolysaccharide (LPS). {ECO:0000269|PubMed:24863067}.
Developmental stage:
Protein families:Short-chain dehydrogenases/reductases (SDR) family