SARM1_MOUSE   Q6PDS3


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UniProt:Q6PDS3

Recommended name:NAD(+) hydrolase SARM1

EC number:EC 3.2.2.6

Alternative names:(NADase SARM1) (NADP(+) hydrolase SARM1) (Sterile alpha and TIR motif-containing protein 1)

Cleaved into:

GeneID:237868

Gene names  (primary ):Sarm1

Gene names  (synonym ):Kiaa0524

Gene names  (ORF ):

Length:724

Mass:79606

Sequence:MVLTLLFSAYKLCRFFTMSGPRPGADRLTVPGPDRSGGASPWWAAGGRGSREVSPGVGTEVQGALERSLPELQQALSELKQASAARAVGAGLAEVFQLVEEAWLLPAVGREVAQGLCDAIRLDGGLDLLLRLLQAPELETRVQAARLLEQILVAENRDRVARIGLGVILNLAKEREPVELARSVAGILEHMFKHSEETCQRLVAAGGLDAVLYWCRRTDPALLRHCALALANCALHGGQTVQRCMVEKRAAEWLFPLAFSKEDELLRLHACLAVAVLATNKEVEREVEHSGTLALVEPLVASLDPGRFARCLVDASDTSQGRGPDDLQSLVLLLDSSRLEAQCIGAFYLCAEAAIKSLQGKTKVFSDIGAIQSLKRLVSYSTNGTTSALAKRALRLLGEEVPRRILPCVASWKEAEVQTWLQQIGFSQYCENFREQQVDGDLLLRLTDEELQTDLGMKSSITRKRFFRELTELKTFASYATCDRSNLADWLGSLDPRFRQYTYGLVSCGLDRSLLHRVSEQQLLEDCGIRLGVHRTRILSAAREMLHSPLPCTGGKLSGDTPDVFISYRRNSGSQLASLLKVHLQLHGFSVFIDVEKLEAGKFEDKLIQSVIAARNFVLVLSAGALDKCMQDHDCKDWVHKEIVTALSCGKNIVPIIDGFEWPEPQALPEDMQAVLTFNGIKWSHEYQEATIEKIIRFLQGRPSQDSSAGSDTSLEGATPMGLP

Tissue specificity:Widely expressed in the brain and neurons (at protein level). {ECO:0000269|PubMed:21555464}.

Induction:Down-regulated in sciatic nerve of mice with diabetic peripheral neuropathy (at protein level). {ECO:0000269|PubMed:31439642}.

Developmental stage:

Protein families:SARM1 family


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