KFA_MOUSE Q8K4H1
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UniProt:Q8K4H1
Recommended name:Kynurenine formamidase
EC number:EC 3.5.1.9
Alternative names:(KFA) (KFase) (Arylformamidase) (N-formylkynurenine formamidase) (FKF)
Cleaved into:
GeneID:71562
Gene names (primary ):Afmid
Gene names (synonym ):
Gene names (ORF ):
Length:305
Mass:34229
Sequence:MAFPSLSAGQNPWRNLSSEELEKQYSPSRWVIHTKPEEVVGNFVQIGSQATQKARATRRNQLDVPYGDGEGEKLDIYFPDEDSKAFPLFLFLHGGYWQSGSKDDSAFMVNPLTAQGIVVVIVAYDIAPKGTLDQMVDQVTRSVVFLQRRYPSNEGIYLCGHSAGAHLAAMVLLARWTKHGVTPNLQGFLLVSGIYDLEPLIATSQNDPLRMTLEDAQRNSPQRHLDVVPAQPVAPACPVLVLVGQHDSPEFHRQSKEFYETLLRVGWKASFQQLRGVDHFDIIENLTREDDVLTQIILKTVFQKL
Tissue specificity:Highly expressed in liver. Expressed in kidney. Weakly or not expressed in other tissues. {ECO:0000269|PubMed:12411446}.
Induction:Down-regulated upon IL2-mediated activation. Transcriptional activation correlates with reduced histone acetylation. {ECO:0000269|PubMed:12411446}.
Developmental stage:
Protein families:Kynurenine formamidase family