TP4A3_MOUSE Q9D658
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UniProt:Q9D658
Recommended name:Protein tyrosine phosphatase type IVA 3
EC number:EC 3.1.3.48
Alternative names:(Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3)
Cleaved into:
GeneID:19245
Gene names (primary ):Ptp4a3
Gene names (synonym ):Prl3
Gene names (ORF ):
Length:173
Mass:19652
Sequence:MARMNRPAPVEVSYRHMRFLITHNPSNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLLKAKFYNDPGSCVAVHCVAGLGRAPVLVALALIESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM
Tissue specificity:Present in the small intestine, where it is located in the differentiated epithelial cells of the villus but not in the proliferating crypt cells (at protein level). Expressed in heart and skeletal muscle, and at lower levels in lung, spleen and testis. {ECO:0000269|PubMed:15161639, ECO:0000269|PubMed:9514946}.
Induction:Down-regulated upon skeletal muscle denervation. {ECO:0000269|PubMed:15673457}.
Developmental stage:
Protein families:Protein-tyrosine phosphatase family