TP4A3_MOUSE   Q9D658


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UniProt:Q9D658

Recommended name:Protein tyrosine phosphatase type IVA 3

EC number:EC 3.1.3.48

Alternative names:(Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3)

Cleaved into:

GeneID:19245

Gene names  (primary ):Ptp4a3

Gene names  (synonym ):Prl3

Gene names  (ORF ):

Length:173

Mass:19652

Sequence:MARMNRPAPVEVSYRHMRFLITHNPSNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLLKAKFYNDPGSCVAVHCVAGLGRAPVLVALALIESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM

Tissue specificity:Present in the small intestine, where it is located in the differentiated epithelial cells of the villus but not in the proliferating crypt cells (at protein level). Expressed in heart and skeletal muscle, and at lower levels in lung, spleen and testis. {ECO:0000269|PubMed:15161639, ECO:0000269|PubMed:9514946}.

Induction:Down-regulated upon skeletal muscle denervation. {ECO:0000269|PubMed:15673457}.

Developmental stage:

Protein families:Protein-tyrosine phosphatase family


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