FFAR2_MOUSE Q8VCK6
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UniProt:Q8VCK6
Recommended name:Free fatty acid receptor 2
EC number:
Alternative names:(G-protein coupled receptor 43) (Leukocyte-specific STAT-induced GPCR)
Cleaved into:
GeneID:233079
Gene names (primary ):Ffar2
Gene names (synonym ):Gpr43 Lssig
Gene names (ORF ):
Length:330
Mass:37124
Sequence:MTPDWHSSLILTAYILIFLTGLPANLLALRAFMGRVRQPQPAPVHILLLNLTLADLLLLLLLPFRIVEAASNFRWYLPKIVCALTGFGFYSSIYCSTWLLAGISMERYLGVAFPVQYKLSRRPLYGVIAALVAWIMSFGHCTIVIIVQYLNSTEQVGTENQITCYENFTQEQLDVVLPVRLELCLVLFFVPMAVTIFCYWRFVWIMLTQPHVGAQRRRRAVGLAVVTLLNFLVCFGPYNMSHLVGFYLRQSPSWRVEAVVFSSLNASLDPLLFYFSSSVVRRAFGKGLLLIRNPASSMLGRGAKETVEGTKMDRGGSQAEGVQSSEFVTE
Tissue specificity:Highly expressed in hematopoietic tissues, such as spleen and bone marrow, with highest levels in a subset of immune cells, including monocytes or neutrophils. Expressed in adipose tissues with high expression in differentiating adipocytes. Expressed by intestinal endocrine cells. {ECO:0000269|PubMed:12393494, ECO:0000269|PubMed:16123168, ECO:0000269|PubMed:22190648}.
Induction:During differentiation of leukocytes. This induction is STAT3-dependent. Up-regulated in adipose tissues by high-fat diet. {ECO:0000269|PubMed:12393494, ECO:0000269|PubMed:16123168}.
Developmental stage:
Protein families:G-protein coupled receptor 1 family