FFAR2_MOUSE   Q8VCK6


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UniProt:Q8VCK6

Recommended name:Free fatty acid receptor 2

EC number:

Alternative names:(G-protein coupled receptor 43) (Leukocyte-specific STAT-induced GPCR)

Cleaved into:

GeneID:233079

Gene names  (primary ):Ffar2

Gene names  (synonym ):Gpr43 Lssig

Gene names  (ORF ):

Length:330

Mass:37124

Sequence:MTPDWHSSLILTAYILIFLTGLPANLLALRAFMGRVRQPQPAPVHILLLNLTLADLLLLLLLPFRIVEAASNFRWYLPKIVCALTGFGFYSSIYCSTWLLAGISMERYLGVAFPVQYKLSRRPLYGVIAALVAWIMSFGHCTIVIIVQYLNSTEQVGTENQITCYENFTQEQLDVVLPVRLELCLVLFFVPMAVTIFCYWRFVWIMLTQPHVGAQRRRRAVGLAVVTLLNFLVCFGPYNMSHLVGFYLRQSPSWRVEAVVFSSLNASLDPLLFYFSSSVVRRAFGKGLLLIRNPASSMLGRGAKETVEGTKMDRGGSQAEGVQSSEFVTE

Tissue specificity:Highly expressed in hematopoietic tissues, such as spleen and bone marrow, with highest levels in a subset of immune cells, including monocytes or neutrophils. Expressed in adipose tissues with high expression in differentiating adipocytes. Expressed by intestinal endocrine cells. {ECO:0000269|PubMed:12393494, ECO:0000269|PubMed:16123168, ECO:0000269|PubMed:22190648}.

Induction:During differentiation of leukocytes. This induction is STAT3-dependent. Up-regulated in adipose tissues by high-fat diet. {ECO:0000269|PubMed:12393494, ECO:0000269|PubMed:16123168}.

Developmental stage:

Protein families:G-protein coupled receptor 1 family


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