ENTP5_MOUSE Q9WUZ9
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UniProt:Q9WUZ9
Recommended name：Ectonucleoside triphosphate diphosphohydrolase 5
EC number：EC 3.6.1.6
Alternative names：(NTPDase 5) (CD39 antigen-like 4) (ER-UDPase) (Guanosine-diphosphatase ENTPD5) (GDPase ENTPD5) (Nucleoside diphosphatase) (Uridine-diphosphatase ENTPD5) (UDPase ENTPD5)
Cleaved into：
GeneID：12499
Gene names (primary )：Entpd5
Gene names (synonym )：Cd39l4
Gene names (ORF )：
Length：427
Mass：47102
Sequence：MATSWGAVFMLIIACVGSTVFYREQQTWFEGVFLSSMCPINVSAGTFYGIMFDAGSTGTRIHVYTFVQKTAGQLPFLEGEIFDSVKPGLSAFVDQPKQGAETVQELLEVAKDSIPRSHWERTPVVLKATAGLRLLPEQKAQALLLEVEEIFKNSPFLVPDGSVSIMDGSYEGILAWVTVNFLTGQLHGRGQETVGTLDLGGASTQITFLPQFEKTLEQTPRGYLTSFEMFNSTFKLYTHSYLGFGLKAARLATLGALEAKGTDGHTFRSACLPRWLEAEWIFGGVKYQYGGNQEGEMGFEPCYAEVLRVVQGKLHQPEEVRGSAFYAFSYYYDRAADTHLIDYEKGGVLKVEDFERKAREVCDNLGSFSSGSPFLCMDLTYITALLKDGFGFADGTLLQLTKKVNNIETGWALGATFHLLQSLGITS
Tissue specificity：Ubiquitous.
Induction：Expressed in response to phosphoinositide 3-kinase (PI3K) signaling. Activation of PI3K results in FOXO phosphorylation by AKT1 and loss of ENTPD5 transcriptional repression. Up-regulated in PTEN-deficient cells. {ECO:0000269|PubMed:21074248}.
Developmental stage：
Protein families：GDA1/CD39 NTPase family