STAU2_MOUSE Q8CJ67
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UniProt:Q8CJ67
Recommended name：Double-stranded RNA-binding protein Staufen homolog 2
EC number：
Alternative names：
Cleaved into：
GeneID：29819
Gene names (primary )：Stau2
Gene names (synonym )：
Gene names (ORF )：
Length：570
Mass：62535
Sequence：MANPKEKTPVCLVNELARFHSIQPQYKLLNESGPAHSKMFSVQLSLGEQTWESEGSSIKKAQQAVANKALTESTLPKPVQKPPKSNVNNNPGSITPTVELNGLAMKRGEPAIYRPLDPKPFPNYRANYNFRGMYNQRYHCPMPKIFYVQLTVGNNEFFGEGKTRQAARHNAAMKALQALQNEPIPEKSPQNGESGKEMDDDKDANKSEISLVFEIALKRNMPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAATTVLQELKKLPPLPVVEKPKLFFKKRPKTIVKAGPDYGQGMNPISRLAQIQQARKEKEPDYILLSERGMPRRREFVMQVKVGNEVATGTGPNKKIAKKNAAEAMLLQLGYKASTSLQDPLDKTGENKGWSGPKPGFPEPTNNTPKGILHLSPDVYQEMEASRHRVTSGTTLSYLSPKDMNQPSSSFFSVSPSSTSSATVARELLMNGTSPTAEAIGLKGSSPTSPCSSVQPSKQLEYLARIQGFQAALSALKQFSEQGLESIDGAVNVEKGSLEKQAKHLREKADNNQAKPASISQDCKKSKSAI
Tissue specificity：Expressed in brain and neurons, where isoform 2 and isoform 3 appear to be the most abundant. Expressed at the neuromuscular junction of the extensor digitorum longus, tibialis anterior and soleus muscles. Expression at neuromuscular junctions is most pronounced in slow-twitch muscle. Also weakly expressed in heart, kidney, ovary and testis. {ECO:0000269|PubMed:12140260, ECO:0000269|PubMed:12859680}.
Induction：Expression in extrasynaptic regions of muscle is induced by denervation. Expression in myoblasts is induced during differentiation into myotubes and by treatment with nerve derived trophic factors such as AGRN (agrin) and NRG1 (neuregulin). {ECO:0000269|PubMed:12859680}.
Developmental stage：
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