FADS1_MOUSE Q920L1
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UniProt:Q920L1
Recommended name：Acyl-CoA (8-3)-desaturase
EC number：EC 1.14.19.44
Alternative names：(Delta(5) fatty acid desaturase) (D5D) (Delta(5) desaturase) (Delta-5 desaturase) (Fatty acid desaturase 1)
Cleaved into：
GeneID：76267
Gene names (primary )：Fads1
Gene names (synonym )：
Gene names (ORF )：
Length：447
Mass：52323
Sequence：MAPDPVPTPGPASAQLRQTRYFTWEEVAQRSGREKERWLVIDRKVYNISDFSRRHPGGSRVISHYAGQDATDPFVAFHINKGLVRKYMNSLLIGELAPEQPSFEPTKNKALTDEFRELRATVERMGLMKANHLFFLVYLLHILLLDVAAWLTLWIFGTSLVPFILCAVLLSTVQAQAGWLQHDFGHLSVFGTSTWNHLLHHFVIGHLKGAPASWWNHMHFQHHAKPNCFRKDPDINMHPLFFALGKVLPVELGREKKKHMPYNHQHKYFFLIGPPALLPLYFQWYIFYFVVQRKKWVDLAWMLSFYARIFFTYMPLLGLKGFLGLFFIVRFLESNWFVWVTQMNHIPMHIDHDRNVDWVSTQLQATCNVHQSAFNNWFSGHLNFQIEHHLFPTMPRHNYHKVAPLVQSLCAKYGIKYESKPLLTAFADIVYSLKESGQLWLDAYLHQ
Tissue specificity：Highly expressed in the adrenal gland, liver, brain, and testis, tissues where lipogenesis and steroidogenesis are active (PubMed:11792729). Expressed in colonic mucosa (PubMed:22534642). {ECO:0000269|PubMed:11792729, ECO:0000269|PubMed:22534642}.
Induction：Expression in liver is down-regulated by dietary PUFA. {ECO:0000269|PubMed:11792729}.
Developmental stage：
Protein families：Fatty acid desaturase type 1 family