TPO_MOUSE   P40226


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UniProt:P40226

Recommended name:Thrombopoietin

EC number:

Alternative names:(C-mpl ligand) (ML) (Megakaryocyte colony-stimulating factor) (Megakaryocyte growth and development factor) (MGDF) (Myeloproliferative leukemia virus oncogene ligand)

Cleaved into:

GeneID:21832

Gene names  (primary ):Thpo

Gene names  (synonym ):

Gene names  (ORF ):

Length:356

Mass:37836

Sequence:MELTDLLLAAMLLAVARLTLSSPVAPACDPRLLNKLLRDSHLLHSRLSQCPDVDPLSIPVLLPAVDFSLGEWKTQTEQSKAQDILGAVSLLLEGVMAARGQLEPSCLSSLLGQLSGQVRLLLGALQGLLGTQLPLQGRTTAHKDPNALFLSLQQLLRGKVRFLLLVEGPTLCVRRTLPTTAVPSSTSQLLTLNKFPNRTSGLLETNFSVTARTAGPGLLSRLQGFRVKITPGQLNQTSRSPVQISGYLNRTHGPVNGTHGLFAGTSLQTLEASDISPGAFNKGSLAFNLQGGLPPSPSLAPDGHTPFPPSPALPTTHGSPPQLHPLFPDPSTTMPNSTAPHPVTMYPHPRNLSQET

Tissue specificity:Found mainly in the liver, kidney and skeletal muscle.

Induction:Expression in the liver and bone marrow displays diurnal rhythmicity (a circadian rhythm that is synchronized with the day/night cycle). {ECO:0000269|PubMed:22284746}.

Developmental stage:

Protein families:EPO/TPO family


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