BLK_MOUSE P16277
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UniProt:P16277
Recommended name：Tyrosine-protein kinase Blk
EC number：EC 2.7.10.2
Alternative names：(B lymphocyte kinase) (p55-Blk)
Cleaved into：
GeneID：12143
Gene names (primary )：Blk
Gene names (synonym )：
Gene names (ORF )：
Length：499
Mass：56674
Sequence：MGLLSSKRQVSEKGKGWSPVKIRTQDKAPPPLPPLVVFNHLAPPSPNQDPDEEERFVVALFDYAAVNDRDLQVLKGEKLQVLRSTGDWWLARSLVTGREGYVPSNFVAPVETLEVEKWFFRTISRKDAERQLLAPMNKAGSFLIRESESNKGAFSLSVKDITTQGEVVKHYKIRSLDNGGYYISPRITFPTLQALVQHYSKKGDGLCQKLTLPCVNLAPKNLWAQDEWEIPRQSLKLVRKLGSGQFGEVWMGYYKNNMKVAIKTLKEGTMSPEAFLGEANVMKTLQHERLVRLYAVVTREPIYIVTEYMARGCLLDFLKTDEGSRLSLPRLIDMSAQVAEGMAYIERMNSIHRDLRAANILVSETLCCKIADFGLARIIDSEYTAQEGAKFPIKWTAPEAIHFGVFTIKADVWSFGVLLMEIVTYGRVPYPGMSNPEVIRSLEHGYRMPCPETCPPELYNDIITECWRGRPEERPTFEFLQSVLEDFYTATEGQYELQP
Tissue specificity：Expressed in immature Vgamma2 gamma-delta T-cells (at protein level) (PubMed:23562159). Expressed in the B-cell lineage (PubMed:2404338, PubMed:1537861). {ECO:0000269|PubMed:1537861, ECO:0000269|PubMed:23562159, ECO:0000269|PubMed:2404338}.
Induction：Expression increases during B-cell differentiation and is under the control of the B-cell specific transcription factors PAX5 and NF-kappa-B. {ECO:0000269|PubMed:7608542, ECO:0000269|PubMed:8195169, ECO:0000269|PubMed:9660839}.
Developmental stage：
Protein families：Protein kinase superfamily, Tyr protein kinase family, SRC subfamily