NAMPT_MOUSE Q99KQ4
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UniProt:Q99KQ4
Recommended name：Nicotinamide phosphoribosyltransferase
EC number：EC 2.4.2.12
Alternative names：(NAmPRTase) (Nampt) (Pre-B-cell colony-enhancing factor 1 homolog) (PBEF) (Visfatin)
Cleaved into：
GeneID：59027
Gene names (primary )：Nampt
Gene names (synonym )：Pbef1
Gene names (ORF )：
Length：491
Mass：55447
Sequence：MNAAAEAEFNILLATDSYKVTHYKQYPPNTSKVYSYFECREKKTENSKVRKVKYEETVFYGLQYILNKYLKGKVVTKEKIQEAKEVYREHFQDDVFNERGWNYILEKYDGHLPIEVKAVPEGSVIPRGNVLFTVENTDPECYWLTNWIETILVQSWYPITVATNSREQKKILAKYLLETSGNLDGLEYKLHDFGYRGVSSQETAGIGASAHLVNFKGTDTVAGIALIKKYYGTKDPVPGYSVPAAEHSTITAWGKDHEKDAFEHIVTQFSSVPVSVVSDSYDIYNACEKIWGEDLRHLIVSRSTEAPLIIRPDSGNPLDTVLKVLDILGKKFPVTENSKGYKLLPPYLRVIQGDGVDINTLQEIVEGMKQKKWSIENVSFGSGGALLQKLTRDLLNCSFKCSYVVTNGLGVNVFKDPVADPNKRSKKGRLSLHRTPAGNFVTLEEGKGDLEEYGHDLLHTVFKNGKVTKSYSFDEVRKNAQLNIEQDVAPH
Tissue specificity：Ubiquitously expressed in lymphoid and non-lymphoid tissues. {ECO:0000269|PubMed:12555668}.
Induction：Expression shows a diurnal pattern of oscillation across the 24-hour light-dark cycle in liver, with a reduction in levels before the onset of the dark period (at protein level). Expression shows a diurnal pattern of oscillation in white adipose tissue (WAT), peaking at the beginning of the dark period. Up-regulated during polyclonal immune responses. {ECO:0000269|PubMed:12555668, ECO:0000269|PubMed:19299583}.
Developmental stage：
Protein families：NAPRTase family