TIMP3_MOUSE P39876
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UniProt:P39876
Recommended name:Metalloproteinase inhibitor 3
EC number:
Alternative names:(Tissue inhibitor of metalloproteinases 3) (TIMP-3)
Cleaved into:
GeneID:21859
Gene names (primary ):Timp3
Gene names (synonym ):Sun Timp-3
Gene names (ORF ):
Length:211
Mass:24182
Sequence:MTPWLGLVVLLSCWSLGHWGAEACTCSPSHPQDAFCNSDIVIRAKVVGKKLVKEGPFGTLVYTIKQMKMYRGFSKMPHVQYIHTEASESLCGLKLEVNKYQYLLTGRVYEGKMYTGLCNFVERWDHLTLSQRKGLNYRYHLGCNCKIKSCYYLPCFVTSKNECLWTDMLSNFGYPGYQSKHYACIRQKGGYCSWYRGWAPPDKSISNATDP
Tissue specificity:Highest levels are found in kidney, lung and brain followed by ovary and uterus. Low levels are found in bone.
Induction:Highly induced by phorbol ester (PMA), EGF and transforming growth factor-beta 1. Also induced by dexamethasone.
Developmental stage:
Protein families:Protease inhibitor I35 (TIMP) family