ENPP3_MOUSE   Q6DYE8


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UniProt:Q6DYE8

Recommended name:Ectonucleotide pyrophosphatase/phosphodiesterase family member 3

EC number:EC 3.1.4.1

Alternative names:(E-NPP 3) (Phosphodiesterase I beta) (PD-Ibeta) (Phosphodiesterase I/nucleotide pyrophosphatase 3) (CD antigen CD203c) [Includes: Alkaline phosphodiesterase I (Nucleotide diphosphatase)]

Cleaved into:

GeneID:209558

Gene names  (primary ):Enpp3

Gene names  (synonym ):

Gene names  (ORF ):

Length:874

Mass:98662

Sequence:MDSRLALATEEPIKKDSLKKYKILCVVLLALLVIVSLGLGLGLGLRKPEEQGSCRKKCFDSSHRGLEGCRCDSGCTGRGDCCWDFEDTCVKSTQIWTCNLFRCGENRLETALCSCADDCLQRKDCCADYKTVCQGESPWVTEACASSQEPQCPPGFDLPPVILFSMDGFRAEYLQTWSTLLPNINKLKTCGIHSKYMRAMYPTKTFPNHYTIVTGLYPESHGIIDNNMYDVHLNKNFSLSSVEKSNPAWWSGQPIWLTAMYQGLKAACYYWPGSDVAVNGSFPTIYRNYSNSVPYERRITTLLQWLDLPKADRPSFYTIYVEEPDSAGHSSGPVSAGVIKALQSVDNAFGMLMEGLKQRNLHNCVNIIVLADHGMDQTSCDRVEYMTDYFPKINFYMYQGPAPRIRTRNIPQDFFTFNSEEIVRNLSCRKPDQHFKPYLTPDLPKRLHYAKNVRIDKAHLMVDRQWLAFRSKGSSNCGGGTHGYNNEFKSMEAIFLAHGPSFIEKTVIEPFENIEVYNLLCDLLHIEPAPNNGTHGSLNHLLKTPFYKPSHAGELSTPADCGFTTPLPTDPLDCSCPALQNTPGLEEQANQRLNLSEGEVAATVKANLPFGRPRVMQKNGDHCLLYHRDYISGYGKAMKMPMWSSYTVLKPGDTSSLPPTVPDCLRADVRVAPSESQKCSFYLADKNITHGFLYPAIKGTNESRYDALITSNLVPMYKEFKKMWDYFHEVLLIKYAIERNGLNVVSGPIFDYNYDGHFDAPDEITQYVAGTDVPIPTHYFVVLTSCKDQTHTPDSCPGWLDVLPFIVPHRPTNIESCSENKTEDLWVEERFQAHAARVRDVELLTGLDFYQEKAQPVSQILQLKTYLPTFETII

Tissue specificity:Detected at the tip of villi in the small intestine (PubMed:28225814). Detected on basophils and mast cells (at protein level) (PubMed:25692702). Detected in the epithelial layer of the small intestine; expression is higher in the proximal part and lower in the distal part of the small intestine (PubMed:28225814). {ECO:0000269|PubMed:25692702, ECO:0000269|PubMed:28225814}.

Induction:In bone marrow-derived mast cells and basophils, induced by activation of the high affinity immunoglobulin epsilon receptor 1 (Fc epsilon RI). {ECO:0000269|PubMed:25692702}.

Developmental stage:

Protein families:


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