CEA20_MOUSE   Q9D2Z1


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UniProt:Q9D2Z1

Recommended name:Carcinoembryonic antigen-related cell adhesion molecule 20

EC number:

Alternative names:

Cleaved into:

GeneID:71601

Gene names  (primary ):Ceacam20

Gene names  (synonym ):

Gene names  (ORF ):

Length:577

Mass:63444

Sequence:MELAGFHCCSWTVILLSALLPTTWRPPAAAHFIHRADLLSNTQMERAPLAKLTLTVNQSTVTEQREMAVFYCNTNADNITIHWVSNNSLLVLNERMKLSADNKTLTILIVQREDSGSYLCEVQHGFEVQRSNTASLTVNYGPDPVSIKLDSGVAAGDVVEVMEGNTVNFRVEAQSSPVPAYAWYLPSDFIQPPTTGTFTIDAVSREHEGMYRCLVSNPVTNLSRLGVVKVQVLEKVTAPNIEFPTLALVENATSVTLTCKTSHQRVGVHWFLKGQPLRPSDRLTLSSQNRTLTIHGLQRDDIGPYECEVWNWGSQARSVPLKLTINYGPDQVEITQGPASGVVSTIEAMLNSSLTLYCRADSIPGARYQWTHEHSSKVLDGEQLSIEALRQEHQGIYSCTSSNDVTGLARSASVLVMVVGLQSSSMSPGAIAGIVIGILVAIALAIGLGYFLYSTKDRWTRRRSASDTTSSNTIPPTSVMQSTPESRHNKPMTVYDNTPKPEGEARGKKMWSLPRDSPEQFYEKKPPSAAPEGPRKPLPQIPKQPLMPPGPGRNEESNYEKLLNSNHSLYCKITPSA

Tissue specificity:Strongly expressed in the small intestine and colon (at protein level) (PubMed:25908210, PubMed:26195794). Minimal expression in other tissues (at protein level) (PubMed:26195794). Highly expressed in cecum, colon, ileum, jejunum, and testis, and also detected at lower levels in salivary gland and thymus (PubMed:16139472). {ECO:0000269|PubMed:16139472, ECO:0000269|PubMed:25908210, ECO:0000269|PubMed:26195794}.

Induction:In intestinal epithelium, up-regulated in the presence of Gram-positive commensal gut bacteria. May also be up-regulated by interferon gamma (IFNG) and butyrate (a product of bacterial fermentation). {ECO:0000269|PubMed:25908210}.

Developmental stage:

Protein families:Immunoglobulin superfamily, CEA family


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