TRIB3_MOUSE Q8K4K2
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UniProt:Q8K4K2
Recommended name:Tribbles homolog 3
EC number:
Alternative names:(TRB-3) (Neuronal cell death-inducible putative kinase)
Cleaved into:
GeneID:228775
Gene names (primary ):Trib3
Gene names (synonym ):Nipk Trb3
Gene names (ORF ):
Length:354
Mass:39023
Sequence:MRATPLAASADVSCRKKPLEFDDNIDAKCPVLKRVRDEPEPGPLPSLLPPSPPPASDLSPAVAPATRLGPYILLEREQGSCSYRALHCPTGTEYTCKVYPASEAQAVLAPYARLPTHQHVARPTEVLLGSRLLYIFFTKTHGDLHSLVRSRRGIPESEAAGLFRQMASAVAHCHKHGLVLRDLKLRRFVFSNCERTKLVLENLEDACVMTGSDDSLWDKHACPAYVGPEILSSRPSYSGKAADVWSLGVALFTMLAGRYPFHDSEPVLLFGKIRRGTFALPEGLSAPARCLIRCLLRKEPSERLVALGILLHPWLREDHGRVSPPQSDRREMDQVVPDGPQLEEAEEGEVGLYG
Tissue specificity:Highly expressed in liver. Not detected in heart, brain, spleen, lung, skeletal muscle, kidney or testis. {ECO:0000269|PubMed:12749859}.
Induction:In liver under fasting conditions and by thapsigargin (PubMed:12749859, PubMed:12791994). Expression is activated by ATF4 in reponse to stress (PubMed:17369260). {ECO:0000269|PubMed:12749859, ECO:0000269|PubMed:12791994, ECO:0000269|PubMed:17369260}.
Developmental stage:
Protein families:Protein kinase superfamily, CAMK Ser/Thr protein kinase family, Tribbles subfamily