ACOT3_MOUSE Q9QYR7
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UniProt:Q9QYR7
Recommended name：Acyl-coenzyme A thioesterase 3
EC number：EC 3.1.2.2
Alternative names：(Acyl-CoA thioesterase 3) (PTE-Ia) (Peroxisomal acyl-coenzyme A thioester hydrolase 2a) (Peroxisomal long-chain acyl-CoA thioesterase 2)
Cleaved into：
GeneID：171281
Gene names (primary )：Acot3
Gene names (synonym )：Pte1a Pte2 Pte2a
Gene names (ORF )：
Length：432
Mass：47490
Sequence：MHAFTTQNPNRMAPTVILEPAGGCLCDQPVHIAVRGLAPEQPVTLRSVLRDEKGALFRAHARYRADSHGELDLARTPALGGSFSGLEPMGLLWAMEPDRPFWRLIKRDVQTPFVVELEVLDGHEPDGGQRLARAVHERHFMAPGVRRVPVREGRVRATLFLPPGTGPFPGIIDLFGIGSGLLEYRASLLAGKGFAVMALAYNNYEDLPKDMDIIHLEYFEEAVTYLLSHPQVTGSGVGVLGISKGGELGFAMASFLKNITAAVIINGSISNIGGNLQYKDETVPSVGINTKRVKRTKDGLKDIVDLLNNPLEGPDQKSLIPVERSDTAFLFLVGQDDHNWKSEFYAREASKRLQAHGKEKPQIICYPETGHHIEPPYFPLCKASLNSLVGGPVIWGGEPRAHAMAQVDAWQQLQTFFHNHLDGKKKTIPAKL
Tissue specificity：Widely expressed. Highly expressed in the kidney, expressed at low level in the liver. Isoform 2 is expressed in the kidney, but not in the liver. Isoform 1 is liver-specific (PubMed:10567408). Highly expressed in kidney (at protein level) (PubMed:15007068). {ECO:0000269|PubMed:10567408, ECO:0000269|PubMed:15007068}.
Induction：In the liver and kidney, by peroxisome proliferator (such as Clofibrate) treatment, via the peroxisome proliferator-activated receptors (PPARs) or fasting for 24 hours.
Developmental stage：
Protein families：C/M/P thioester hydrolase family