ACOT4_MOUSE Q8BWN8
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UniProt:Q8BWN8
Recommended name:Peroxisomal succinyl-coenzyme A thioesterase
EC number:EC 3.1.2.3
Alternative names:(Acyl-coenzyme A thioesterase 4) (Acyl-CoA thioesterase 4) (PTE-2b) (Peroxisomal acyl coenzyme A thioester hydrolase Ib) (Peroxisomal long-chain acyl-CoA thioesterase Ib) (PTE-Ib)
Cleaved into:
GeneID:171282
Gene names (primary ):Acot4
Gene names (synonym ):Pte1b Pte2b
Gene names (ORF ):
Length:421
Mass:46481
Sequence:MAATLSVEPTGRSCWDEPLSIAVRGLAPEQPVTLRSVLRDEKGALFRAHARYRADSHGELDLARVPALGGSFSGLEPMGLLWAMEPDRPFWRLIKRDVQTPFLVELEVLDGHEPDGGRRLARTVHERHFMAPGVRRVPVREGRVRATLFLPPGQGPFPGIIDVYGVGGGLLEYRAGLVAGHGFATLALAFYDFEDLPKELNVIEVDYFEEAVRYMLRHPKVKGPDIGLLGLSLGADVCLIMASFLNNVSATVSINGSAFSGNRHIKYKQTMIPPLGHDLRRMKVAFSGILDIVDIRNDAVGGCENPSMIPIEKAKGPILFVAGQDDHCWRSELYTQIASDRLQAHGKERPQVLSYPGTGHYIEPPYFPMCPASLHKIVNEAVIWGGEVKAHSKAQIDAWKQILFFFGKHLGSTHSRASCRL
Tissue specificity:Mainly expressed in liver and kidney. Weakly expressed in other tissues including intestine, adrenal gland and adipose tissues. {ECO:0000269|PubMed:10567408, ECO:0000269|PubMed:16141203, ECO:0000269|PubMed:16940157}.
Induction:In the liver, by peroxisome proliferator (Clofibrate) treatment, via the peroxisome proliferator-activated receptors (PPARs) or fasting for 24 hours. {ECO:0000269|PubMed:10567408}.
Developmental stage:
Protein families:C/M/P thioester hydrolase family