ACOT2_MOUSE   Q9QYR9


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UniProt:Q9QYR9

Recommended name:Acyl-coenzyme A thioesterase 2, mitochondrial

EC number:EC 3.1.2.2

Alternative names:(Acyl-CoA thioesterase 2) (Acyl coenzyme A thioester hydrolase) (MTE-I) (Very-long-chain acyl-CoA thioesterase)

Cleaved into:

GeneID:171210

Gene names  (primary ):Acot2

Gene names  (synonym ):Mte1

Gene names  (ORF ):

Length:453

Mass:49657

Sequence:MVASSFAVLRASRLCQQDWKSWARLFVPPPLSTGGRTTWARTNATLSVEPEGRSCWDEPLSIAVRGLAPEQPVTLRSALRDEKGALFRAHARYRADAGGELNLARAPALGGSFSGLEPMGLLWAMEPERPLWRLIKRDVQTPFLVELEVLDGHEPDGGQRLAQAVHERHFLAPGVRRVPVREGRVRATLFLPPEPGPFPGIIDLFGVGGGLLEYRASLLAGKGFAVMALAYYNYDDLPKSIETMHMEYFEEAVNYLRSHPEVKGPGIGLLGISKGGELGLAMASFLKGITAAVVINGSVAAVGNTISYKDETIPPVSLLRNQVKMTKDGLLDVVEALQSPLVDKKSFIPVERSDTTFLFLVGQDDHNWKSEFYADEISKRLQAHGKEKPQIICYPAAGHYIEPPYFPLCSAGMHLLVGANITFGGEPRAHAVAQVDAWQQLQTFFHKQLGSKS

Tissue specificity:Highly expressed in brown and white adipose tissue, muscle, heart, kidney, lung, adrenal gland and spleen; weakly expressed in intestine, testis and brain. {ECO:0000269|PubMed:10567408, ECO:0000269|PubMed:11330065}.

Induction:In the liver, by peroxisome proliferator (Clofibrate) treatment, via the peroxisome proliferator-activated receptors (PPARs) or fasting for 24 hours. {ECO:0000269|PubMed:11330065}.

Developmental stage:

Protein families:C/M/P thioester hydrolase family