ESR2_MOUSE O08537
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UniProt:O08537
Recommended name：Estrogen receptor beta
EC number：
Alternative names：(ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Cleaved into：
GeneID：13983
Gene names (primary )：Esr2
Gene names (synonym )：Estrb Nr3a2
Gene names (ORF )：
Length：530
Mass：59070
Sequence：MEIKNSPSSLTSPASYNCSQSILPLEHGPIYIPSSYVESRHEYSAMTFYSPAVMNYSVPSSTGNLEGGPVRQTASPNVLWPTSGHLSPLATHCQSSLLYAEPQKSPWCEARSLEHTLPVNRETLKRKLGGSGCASPVTSPSAKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRIVRRQRSASEQVHCLNKAKRTSGHTPRVKELLLNSLSPEQLVLTLLEAEPPNVLVSRPSMPFTEASMMMSLTKLADKELVHMIGWAKKIPGFVELSLLDQVRLLESCWMEVLMVGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTARFRELKLQHKEYLCVKAMILLNSSMYPLATASQEAESSRKLTHLLNAVTDALVWVISKSGISSQQQSVRLANLLMLLSHVRHISNKGMEHLLSMKCKNVVPVYDLLLEMLNAHTLRGYKSSISGSECCSTEDSKSKEGSQNLQSQ
Tissue specificity：Expressed in prostate, ovary, Leydig cells and in epithelium of the efferent ductules and of the initial segment of the epididymis. {ECO:0000269|PubMed:9607809}.
Induction：Isoforms 1 and 2 are down-regulated by 17-beta-estradiol. {ECO:0000269|PubMed:11878304}.
Developmental stage：
Protein families：Nuclear hormone receptor family, NR3 subfamily