APEL_MOUSE Q9R0R4
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UniProt:Q9R0R4
Recommended name:Apelin
EC number:
Alternative names:(APJ endogenous ligand)
Cleaved into:Apelin-36; Apelin-31; Apelin-28; Apelin-13
GeneID:30878
Gene names (primary ):Apln
Gene names (synonym ):Apel
Gene names (ORF ):
Length:77
Mass:8658
Sequence:MNLRLCVQALLLLWLSLTAVCGVPLMLPPDGTGLEEGSMRYLVKPRTSRTGPGAWQGGRRKFRRQRPRLSHKGPMPF
Tissue specificity:Expressed in extraembryonic visceral endoderm and in the primitive streak at 6.5 and 7.5 dpc (PubMed:28854362). Expressed in the anterior visceral yolk sac at 8.25 dpc (PubMed:28854362). Expressed weakly in the embryonic heart at 11.5 dpc (PubMed:26611206). Expressed in the adult heart (PubMed:26611206). Expressed in endothelial cells and cardiomyocytes and weakly expressed in fibroblasts (PubMed:26611206). {ECO:0000269|PubMed:26611206, ECO:0000269|PubMed:28854362}.
Induction:Not up-regulated following myocardial infarction (MI) (at protein level) (PubMed:26611206). {ECO:0000269|PubMed:26611206}.
Developmental stage:
Protein families:Apelin family