OSTB_MOUSE Q80WK2
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UniProt:Q80WK2
Recommended name:Organic solute transporter subunit beta
EC number:
Alternative names:(OST-beta) (Solute carrier family 51 subunit beta)
Cleaved into:
GeneID:330962
Gene names (primary ):Slc51b
Gene names (synonym ):Ostb
Gene names (ORF ):
Length:128
Mass:14684
Sequence:MDHSAEKAAANAEVPQELLEEMLWYFRAEDAAPWNYSILVLAVLVVMTSMFLLRRSILANRNRKKQPQDKETPEDLHLDDSIMKENNSQVFLRETLISEKPDLAPGEPELKEKDSSLVFLPDPQETES
Tissue specificity:Present at high level in ileum. In ileum, it is restricted to the apical domain on the mature villus enterocytes with little detectable expression in the goblet cells or crypt enterocytes (at protein level). Expressed in kidney but not in heart, brain, liver, spleen, embryo, lung, thymus, ovary nor testis. {ECO:0000269|PubMed:15563450}.
Induction:Positively regulated via the bile acid-activated nuclear receptor farnesoid X receptor (NR1H4/FXR). {ECO:0000269|PubMed:16357058, ECO:0000269|PubMed:16628672}.
Developmental stage:
Protein families:OST-beta family