OSTB_MOUSE   Q80WK2


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UniProt:Q80WK2

Recommended name:Organic solute transporter subunit beta

EC number:

Alternative names:(OST-beta) (Solute carrier family 51 subunit beta)

Cleaved into:

GeneID:330962

Gene names  (primary ):Slc51b

Gene names  (synonym ):Ostb

Gene names  (ORF ):

Length:128

Mass:14684

Sequence:MDHSAEKAAANAEVPQELLEEMLWYFRAEDAAPWNYSILVLAVLVVMTSMFLLRRSILANRNRKKQPQDKETPEDLHLDDSIMKENNSQVFLRETLISEKPDLAPGEPELKEKDSSLVFLPDPQETES

Tissue specificity:Present at high level in ileum. In ileum, it is restricted to the apical domain on the mature villus enterocytes with little detectable expression in the goblet cells or crypt enterocytes (at protein level). Expressed in kidney but not in heart, brain, liver, spleen, embryo, lung, thymus, ovary nor testis. {ECO:0000269|PubMed:15563450}.

Induction:Positively regulated via the bile acid-activated nuclear receptor farnesoid X receptor (NR1H4/FXR). {ECO:0000269|PubMed:16357058, ECO:0000269|PubMed:16628672}.

Developmental stage:

Protein families:OST-beta family


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