HEPC_MOUSE Q9EQ21
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UniProt:Q9EQ21
Recommended name：Hepcidin
EC number：
Alternative names：
Cleaved into：
GeneID：84506
Gene names (primary )：Hamp
Gene names (synonym )：Hamp1 Hepc Hepc1
Gene names (ORF )：
Length：83
Mass：9352
Sequence：MALSTRTQAACLLLLLLASLSSTTYLHQQMRQTTELQPLHGEESRADIAIPMQKRRKRDTNFPICIFCCKCCNNSQCGICCKT
Tissue specificity：Highly expressed in the liver and to a much lesser extent in the heart. Secreted in blood (PubMed:15124018). {ECO:0000269|PubMed:11113132, ECO:0000269|PubMed:12729891, ECO:0000269|PubMed:15124018}.
Induction：Regulated in response to changes in circulating iron concentrations, iron stores or the development of inflammation and iron-restricted erythropoiesis. Down-regulated following anemia induced by hemorrhage or hemolysis: down-regulation is mediated by ERFE (PubMed:12370282, PubMed:24880340, PubMed:15124018). The induction of upon inflammation is mediated by IL6 (PubMed:15124018). {ECO:0000269|PubMed:12370282, ECO:0000269|PubMed:15124018, ECO:0000269|PubMed:24880340}.
Developmental stage：
Protein families：Hepcidin family