DDIAS_MOUSE Q6NZG4
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UniProt:Q6NZG4
Recommended name：DNA damage-induced apoptosis suppressor protein
EC number：
Alternative names：(Nitric oxide-inducible gene protein)
Cleaved into：
GeneID：
Gene names (primary )：Ddias
Gene names (synonym )：Noxin
Gene names (ORF )：
Length：898
Mass：99945
Sequence：MNKRRKFLFASVLAVQNSNFIYPSCQRCFSKIILESKRFTCPKCGSSGDTGSTNYRYKLSLKVAESSKLFFITVFGSCLDTFFGLTATGLHRYLGDSIKNLETLDSGRTQSLLTTAVEKCFVGQSFVFGVTNFGDVCGHDSDSSNFQQPCCKHRGEVRTLVASQIILPSPHVKGFTVIAYLHPLLHKKPHCGSQEHSSQSLTSDDSDSDLNNIQGSGNTSWFSESSVGEDFFRYWEPSLELTSSDSQVTSSDDFPASKQIMASGTPNQNRHCISVSEVTSSKNCHDSLQSLWSLHSCMDKNNTTGKLGEELGLPSPVCNSCHESRLSDSHFFPSQMQEPFEEHNLECYSKAEKNDYSQYDIACYQHHEVNTTPILQQRSSAFSLSSLKPEETANPSQNSDSLIWDDLPLSESLNKFLAVVESEVAVTEIDAKNRKQGMDKSIDKCHKNYSRLSLTPWRNTRALNTSCFSLRSSQAMMKDSGKEALFSNCKSNSSPHIQKESKADKTEAAVSIAGSRSDISEDFLPDTCSSALFTSSKDREAFITQKRTSGVLQQRNEISCRPSTSISDCSDLRSRYFTGCGQKLHSGTKGKLAIQNCSKKYSDASDLHKLENKHRWPKKEDDNFTICRKLTYPLETLCSSPESINTSKEMPYRPSNNNLTPSSSGDHEGSYNASADLFDYIAKDKDIGTEITKIPQDNLLPLEVPCTENYPINENRGQPSQKPSLQSISPSRYSRPRSQSDSECDFEESQDFVPCSQSTPVAGFHQRIHGLNGASKILPSIYSNPNANYKNRKNSPLTGQYQATSACSKNVKAFRQKPESPFVSSLTQANVFNHCPAAESLGNDVDEWVPPTTKKVFISDILGFRVMGLRKCLDLHYSPDPKELPRKKLIKVTHKTNI
Tissue specificity：Highly expressed in the testis, spleen and heart. Expressed at high levels in the primary spermatocytes and to a lesser extent in the round spermatids. Also found in the bone marrow, brain, lung, kidney and liver. {ECO:0000269|PubMed:17515607}.
Induction：Strongly induced by a wide range of stress signals: nitric-oxide, gamma- and UV irradiation, hydrogen peroxide, adriamycin and cytokines and this induction is dependent on p53/TP53. Expression is low in resting cells and increases almost 50-fold as the cells progress through the S phase. {ECO:0000269|PubMed:17515607}.
Developmental stage：
Protein families：