ARHGP_MOUSE Q9CWR0
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UniProt:Q9CWR0
Recommended name：Rho guanine nucleotide exchange factor 25
EC number：
Alternative names：(Guanine nucleotide exchange factor GEFT) (Rac/Cdc42/Rho exchange factor GEFT) (RhoA/Rac/Cdc42 guanine nucleotide exchange factor GEFT) (p63RhoGEF)
Cleaved into：
GeneID：52666
Gene names (primary )：Arhgef25
Gene names (synonym )：D10Ertd610e Geft
Gene names (ORF )：
Length：618
Mass：68262
Sequence：MKPPDRPTPGRTDRILGVMGGMLRACAVPGQEGPPERDPLGPGSTKTESDCIEEDQTGQREPEVLAWAPQPESYSIAVSEGSMSASAVSGLAALSGPSSGLSSDPCSPIPPGPVTGLRRWLDHSKHCLSVETEAESGQTGQCENWTLGPTLTTGQELPELTLLTTLLEGPGDKAQPAEEETLSQAPKNEEEQKKMALERSMFVLGELVETERTYEDDLGQIVEGYMATMATQGVPESLRGRDRIVFGNIQQIYEWHRDYFLQELQQCLKDPDWLAQLFIKHERRLHMYVVYCQNKPKSEHVLSEFGDSYFEELRQQLGHRLQLNDLLIKPVQRIMKYQLLLKDFLKYYRRAGKDTEELEQAVEVMCFVPKRCNDMMSLGRLRGFEGKLTAQGKLLGQDTFLVTEPEAGGLLSSRGRERRVFLFEQIIIFSEALGGGGRGGAQPGYVYKNSIKVSCLGLEGNLQGNPCRFALTSRGPEGGIQRYVLQASDPAVSQAWIKQVAQILESQRDFLNALQSPIEYQRRESQTNSLGRPGGPWVGSPGRMRPGDLAQASMHTPINGSLPSLLLLPRGEVSRVLLPLDTQALSDTPQTPHDSPALPTVNTPPCQARLAKLDEDEL
Tissue specificity：Highly expressed in excitable tissues, such as brain, heart and muscle. Elevated expression in hippocampus and cerebellum. {ECO:0000269|PubMed:15322108, ECO:0000269|PubMed:16314529, ECO:0000269|PubMed:16496360}.
Induction：Transcriptionally up-regulated during myogenic differentiation and down-regulated during adipogenic differentiation. Protein levels up-regulated during retinoic acid and dibutyric cAMP-induced outgrowth of neurites. {ECO:0000269|PubMed:16314529, ECO:0000269|PubMed:16496360}.
Developmental stage：
Protein families：