TIKI2_MOUSE B1ATG9
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UniProt:B1ATG9
Recommended name：Metalloprotease TIKI2
EC number：EC 3.4.-.-
Alternative names：(Heart, kidney and adipose-enriched transmembrane protein) (TRAB domain-containing protein 2B)
Cleaved into：
GeneID：666048
Gene names (primary )：Trabd2b
Gene names (synonym )：Gm12824 Hkat Tiki2
Gene names (ORF )：
Length：517
Mass：57368
Sequence：MHAALAGPLLAALLATARARPQPPDGGQCRPPGSQRDLNSFLWTIRRHPPAYLFGTIHVPYTRVWDFIPDNSKAAFQASTHVYFELDLTDPYTISALASCQLLPHGENLQDVLPRELYWRLKRHLDYVKLMIPSWMTPAQRGKGLYADYLFNAIAGNWERKRPVWVMLMVNSLTETDVRSRGVPVLDLYLAQQAEKMKKSTGAVERVEEQCHPLNGLNFSQVLFALNQTLLQHESVRAGSLQAPYTTEDLIKHYNCGDLNAVIFNHDTSQLPNFINTTLPPHEQVTAQEIDSYFRQELIYKRNERMGKRVMALLQENQDKICFFAFGAGHFLGNNTVIDVLRQAGLEVDHTPAGQAIHGPAAVGSPAPPPEITSPASPAPATPAAAVPEATSATPTTPPEEEDPVLSPHLLLPDSLSQLEEFGRQKWRKRLNKHQRPRQFNDLWVRIEDSTTISPPPLPLQPTPSSETTKPFVKSSHQLQQQDAVGPTSSSAPTLGLLHAITASIVAPFLLHSLGPS
Tissue specificity：Highly expressed in heart and kidney. Also found in white and brown adipose tissue. {ECO:0000269|PubMed:23152936}.
Induction：Transiently induced during 3T3-L1 cell differentiation into adipocytes. In vivo, down-regulated by fasting in both white and brown adipose tissues. High-fat diet down-regulates expression in white adipose tissue and up-regulates it in brown adipose tissue. {ECO:0000269|PubMed:23152936}.
Developmental stage：
Protein families：TIKI family