CJ090_MOUSE   D2J0Y4


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UniProt:D2J0Y4

Recommended name:(E2-independent) E3 ubiquitin-conjugating enzyme FATS

EC number:EC 2.3.2.-

Alternative names:(Centrosomal protein C10orf90 homolog) (E2/E3 hybrid ubiquitin-protein ligase FATS) (Fragile-site associated tumor suppressor homolog) (FATS)

Cleaved into:

GeneID:71007

Gene names  (primary ):D7Ertd443e

Gene names  (synonym ):Fats

Gene names  (ORF ):

Length:644

Mass:71521

Sequence:MISPVVISRLIDEKKSMENGAILPQAIAQPQLCPTKPALARRDGVSMHRRFALSPDRLGILTPSDDQGLETEPLSTGDNLGKGSHSGFSSITITARRVGPPASSLVWDTFRDPLCPKCKAKDALFQEPPVLAGDAHLCQHNRPFTCTESPSNGSVEGMKVFQAHSRLSARQDYWVTHTNDNEDSFSSDNSPSRKVPLVFSSCVHFRVSQQCPNAIYYLDKSLSVPLERPQIASPKMHRSVLSLSLRCSSHQLTADGVDSSANGEPISTALSQELSEGKQDLLGPQWGQPQGGHWKESPALVPVHLGSGTCPRTGSPPLENVKFADVGRNQVPVRKEKEDHATCTSSSHTNQLSIHIPGWSYRAETKVLSGSKKQQQEAQRTLPAFPVGQKTIKHFPPEGDSSPSSDGQPSILSESNERQHPYFMIPRVPLPGFYCPLQTGCASLQEDGAVQIETHFPKDYTCCDLVVKLKECEKNEDPTVTPEPSPATPSPSTPEGAQSSDPSEDSYEPLLASSMTLQEALEVHRPQFISRSQERLQKLKRMVQQRKTQQKESLGQKQSLLPVRANKKQFTIPHPLSDNLFKPKERCISEKEMHMRSKRIYNNLPEVKKKKEEQKKRMILQSNRLRAEVFKKQLLDQLLQRNAV

Tissue specificity:Highly expressed in testis. Weak expression found in brain, lung, heart, ovary, thymus, spleen and kidney. {ECO:0000269|PubMed:20843368}.

Induction:Upon DNA damage by agents such as ionizing radiation, UV and actinomycin D. Activated by p53/TP53. {ECO:0000269|PubMed:20843368}.

Developmental stage:

Protein families:


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