ZFAN5_MOUSE O88878
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UniProt:O88878
Recommended name:AN1-type zinc finger protein 5
EC number:
Alternative names:(Zinc finger A20 domain-containing protein 2) (Zinc finger protein 216)
Cleaved into:
GeneID:22682
Gene names (primary ):Zfand5
Gene names (synonym ):Za20d2 Zfp216 Znf216
Gene names (ORF ):
Length:213
Mass:23058
Sequence:MAQETNQTPGPMLCSTGCGFYGNPRTNGMCSVCYKEHLQRQQNSGRMSPMGTASGSNSPTSDSASVQRADAGLNNCEGAAGSTSEKSRNVPVAALPVTQQMTEMSISREDKITTPKTEVSEPVVTQPSPSVSQPSSSQSEEKAPELPKPKKNRCFMCRKKVGLTGFDCRCGNLFCGLHRYSDKHNCPYDYKAEAAAKIRKENPVVVAEKIQRI
Tissue specificity:Expressed in brain, muscle, eye, and heart, lower expression in lung, kidney, and spleen, and very low expression in liver. Expressed in myoblast C2C12 cells (at protein level). {ECO:0000269|PubMed:14754897, ECO:0000269|PubMed:9758550}.
Induction:Up-regulated after TNFSF11 stimulation. Expression also induced by other cytokines such as TNF and IL1B. No significant inhibitory effect on the NF-kappa-B pathway is observed. Expression is increased in both denervation- and fasting-induced muscle atrophy. {ECO:0000269|PubMed:16194934}.
Developmental stage:
Protein families: