PDK1_MOUSE Q8BFP9
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UniProt:Q8BFP9
Recommended name：[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial
EC number：EC 2.7.11.2
Alternative names：[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial (Pyruvate dehydrogenase kinase isoform 1) (PDH kinase 1)
Cleaved into：
GeneID：228026
Gene names (primary )：Pdk1
Gene names (synonym )：
Gene names (ORF )：
Length：434
Mass：48995
Sequence：MRLARLLRGGTSVRPLCAVPCASRSLASASASGSGPASELGVPGQVDFYARFSPSPLSMKQFLDFGSVNACEKTSFMFLRQELPVRLANIMKEISLLPDNLLRTPSVQLVQSWYIQSLQELLDFKDKSAEDAKTIYEFTDTVIRIRNRHNDVIPTMAQGVTEYKESFGVDPVTSQNVQYFLDRFYMSRISIRMLLNQHSLLFGGKGSPSHRKHIGSINPNCDVVEVIKDGYENARRLCDLYYVNSPELELEELNAKSPGQTIQVVYVPSHLYHMVFELFKNAMRATMEHHADKGVYPPIQVHVTLGEEDLTVKMSDRGGGVPLRKIDRLFNYMYSTAPRPRVETSRAVPLAGFGYGLPISRLYAQYFQGDLKLYSLEGYGTDAVIYIKALSTESVERLPVYNKAAWKHYKANHEADDWCVPSREPKDMTTFRSS
Tissue specificity：
Induction：Up-regulated by glucose and palmitate. Up- regulated via the HIF1A signaling pathway in response to hypoxia. {ECO:0000269|PubMed:16517406, ECO:0000269|PubMed:16631612}.
Developmental stage：
Protein families：PDK/BCKDK protein kinase family