IIGP1_MOUSE   Q9QZ85


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UniProt:Q9QZ85

Recommended name:Interferon-inducible GTPase 1

EC number:EC 3.6.5.-

Alternative names:

Cleaved into:

GeneID:60440

Gene names  (primary ):Iigp1

Gene names  (synonym ):Irga6

Gene names  (ORF ):

Length:413

Mass:47572

Sequence:MGQLFSSPKSDENNDLPSSFTGYFKKFNTGRKIISQEILNLIELRMRKGNIQLTNSAISDALKEIDSSVLNVAVTGETGSGKSSFINTLRGIGNEEEGAAKTGVVEVTMERHPYKHPNIPNVVFWDLPGIGSTNFPPNTYLEKMKFYEYDFFIIISATRFKKNDIDIAKAISMMKKEFYFVRTKVDSDITNEADGKPQTFDKEKVLQDIRLNCVNTFRENGIAEPPIFLLSNKNVCHYDFPVLMDKLISDLPIYKRHNFMVSLPNITDSVIEKKRQFLKQRIWLEGFAADLVNIIPSLTFLLDSDLETLKKSMKFYRTVFGVDETSLQRLARDWEIEVDQVEAMIKSPAVFKPTDEETIQERLSRYIQEFCLANGYLLPKNSFLKEIFYLKYYFLDMVTEDAKTLLKEICLRN

Tissue specificity:

Induction:Up-regulated by IFNG, IFNA1 and lipopolysaccharide (LPS) within 20 hours. Transiently up-regulated during the early stages of infection by Listeria monocytogenes. After 6 days expression is back to basal levels. {ECO:0000269|PubMed:11907101, ECO:0000269|PubMed:9862701}.

Developmental stage:

Protein families:TRAFAC class dynamin-like GTPase superfamily, IRG family


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