FER_MOUSE P70451
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UniProt:P70451
Recommended name：Tyrosine-protein kinase Fer
EC number：EC 2.7.10.2
Alternative names：(Proto-oncogene c-Fer) (p94-Fer)
Cleaved into：
GeneID：14158
Gene names (primary )：Fer
Gene names (synonym )：Fert2
Gene names (ORF )：
Length：823
Mass：94579
Sequence：MGFGSDLKNSQEAVLKLQDWELRLLETVKKFMALRIKSDKEYAYTLQNLCNQVDKESTVQVNYVSNVSKSWLLMIQQTEQLSRIMKTHAEDLNSGPLHRLTMMIKDKQQVKKSYVGIHQQIEAEMIKVTKTELEKLKSSYRQLIKEMNSAKEKYKEALAKGKETEKAKERYDKATMKLHMLHNQYVLALKGAQLHQSQYYDTTLPLLLDSVQKMQEEMIKALKGIFDDYSQITSLVTEEIVNVHKEIQMSVEQIDPSTEYNNFIDVHRTTAAKEQEIEFDTSLLEENENLQANEIMWNNLTADSLQVMLKTLAEELTQTQQMLLHKEAAVLELEKRIEESFETCEKKSDIVLLLGQKQALEELKQSVQQLRCTEAKCAAQKALLEQKVQENDGKEPPPVVNYEEDARSVTSMERKERLSKFESIRHSIAGIIKSPKSVLGSSTQVCDVISVGERPLAEHDWYHGAIPRIEAQELLKQQGDFLVRESHGKPGEYVLSVYSDGQRRHFIIQFVDNLYRFEGTGFSNIPQLIDHHFNTKQVITKKSGVVLLNPIPKDKKWVLNHEDVSLGELLGKGNFGEVYKGTLKDKTPVAIKTCKEDLPQELKIKFLQEAKILKQYDHPNIVKLIGVCTQRQPVYIIMELVPGGDFLTFLRKRKDELKLKQLVRFSLDVAAGMLYLESKNCIHRDLAARNCLVGENNTLKISDFGMSRQEDGGVYSSSGLKQIPIKWTAPEALNYGRYSSESDVWSFGILLWETFSLGVCPYPGMTNQQAREQVERGYRMSAPQNCPEEVFTIMMKCWDYKPENRPKFNDLHKELTVIKKMIT
Tissue specificity：Detected in liver and testis. Isoform 4 is detected only in testis (at protein level). Widely expressed. {ECO:0000269|PubMed:10391941, ECO:0000269|PubMed:11134346, ECO:0000269|PubMed:2294399}.
Induction：Up-regulated by insulin in myogenic cells (in vitro). {ECO:0000269|PubMed:12738762}.
Developmental stage：
Protein families：Protein kinase superfamily, Tyr protein kinase family, Fes/fps subfamily