PSB9_MOUSE P28076
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UniProt:P28076
Recommended name:Proteasome subunit beta type-9
EC number:EC 3.4.25.1
Alternative names:(LMP-2d) (Low molecular mass protein 2) (Macropain chain 7) (Multicatalytic endopeptidase complex chain 7) (Proteasome chain 7) (Proteasome subunit beta-1i) (Really interesting new gene 12 protein)
Cleaved into:
GeneID:16912
Gene names (primary ):Psmb9
Gene names (synonym ):Lmp2 Ring12
Gene names (ORF ):
Length:219
Mass:23397
Sequence:MLRAGAPTAGSFRTEEVHTGTTIMAVEFDGGVVVGSDSRVSAGTAVVNRVFDKLSPLHQRIFCALSGSAADAQAIADMAAYQLELHGLELEEPPLVLAAANVVKNISYKYREDLLAHLIVAGWDQREGGQVYGTMGGMLIRQPFTIGGSGSSYIYGYVDAAYKPGMTPEECRRFTTNAITLAMNRDGSSGGVIYLVTITAAGVDHRVILGDELPKFYDE
Tissue specificity:Detected in liver (at protein level). Expressed at high levels in the thymus, spleen, lung, heart and liver. Expressed at moderate levels in the kidney. {ECO:0000269|PubMed:22341445, ECO:0000269|PubMed:8325639}.
Induction:Up-regulated by interferon gamma (at protein level). Up-regulated by IRF1. Up-regulated by heat shock treatment. Down-regulated by EGR1 in neuronal cells. {ECO:0000269|PubMed:15907481, ECO:0000269|PubMed:16452686, ECO:0000269|PubMed:17142736}.
Developmental stage:
Protein families:Peptidase T1B family