OCSTP_MOUSE Q9D611
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UniProt:Q9D611
Recommended name:Osteoclast stimulatory transmembrane protein
EC number:
Alternative names:(OC-STAMP)
Cleaved into:
GeneID:74614
Gene names (primary ):Ocstamp
Gene names (synonym ):
Gene names (ORF ):
Length:498
Mass:54574
Sequence:MRTIRAATEHLFGLGWKFWRLGICKAVVPLQAAWKAFSQPVPASCNELLTQLLLCVSLASLIAGLAHHWLVSLQLYPLGPPALVTSLCGLFVFLSLGLVPPIRCLFVLSVPTLGSKQGRRLLLSYSAANLAVAVVPNVLGNVRAAGQVLSCVTEGSLESLLNTTYQLRQAARELGPASRAGSRSLTFEVEGKGSAFRLHMHTITQEILEDFSGLEFLARAALGTQRVVTGLFLLGLLGESAWYLHRYLTDLRFDNIYATRQLVRQLAQAGATHLLTSPPPWLLQTAQPKLSREELLSCLLRLGLLALLLVATAVTVASDYGAFLLAQAAVAWAQKLPTVPITLTVKYDASYKVLDFILFVLNQPPVESVFASMQRSFQWELRFTPHDCHLPQAQPPRVTAALAAGALQLLAGATLVLQAYAWRLRHTIAASFFPDQEARRLSHLQARLQRRHNQSDHLNKQPGTMATRESRKPGQGTRTLESQGPQAHDSLGPPYDLE
Tissue specificity:Expressed in osteoclast (at protein level). Ubiquitous. Highly expressed in multi-nuclear osteoclast cells compared to mono-nuclear macrophages. Expressed in foreign body giant cells (FBGCs). {ECO:0000269|PubMed:18064667, ECO:0000269|PubMed:20882308, ECO:0000269|PubMed:22337159}.
Induction:Up-regulated during osteoclast and foreign body giant cells (FBGCs) differentiation by TNFSF11 and cytokines. Down-regulated by estrogen. {ECO:0000269|PubMed:18064667, ECO:0000269|PubMed:20882308, ECO:0000269|PubMed:22337159}.
Developmental stage:
Protein families: