AGRE4_MOUSE Q91ZE5
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UniProt:Q91ZE5
Recommended name:Adhesion G protein-coupled receptor E4
EC number:
Alternative names:(EGF-like module receptor 4) (EGF-like module-containing mucin-like hormone receptor-like 4) (F4/80-like-receptor) (Seven-span membrane protein FIRE)
Cleaved into:
GeneID:52614
Gene names (primary ):Adgre4
Gene names (synonym ):Emr4
Gene names (ORF ):
Length:689
Mass:77045
Sequence:MLMGATRDMGSRCLLHASVPGMLLIWSILQMMNISASCPQCNENASCFNSTHCVCKEGFWTGSENRRIIEPHEKCQDINECLLKELVCKDVSYCRNKIGTYICSCVVKYPLFNWVAGIINIDHPDCYVNKSKNTGSKTHTLGVLSEFKSKEEVAKGATKLLRKVEHHILNENSDIPKKDENPLLDIVYETKRCKTMTLLEAGNNTMKVDCTSGFKEHNSGGETAVAFIAYKSLGNLLNGSFFSNEEGFQEVTLNSHIVSGAIRSEVKPVLSEPVLLTLQNIQPIDSRAEHLCVHWEGSEEGGSWSTKGCSHVYTNNSYTICKCFHLSSFAVLMALPHEEDGVLSALSVITYVGLSLSLLCLFLAAITFLLCRPIQNTSTTLHLQLSICLFLADLLFLTGINRTKPKVLCSIIAGMLHYLYLASFMWMFLEGLHLFLTVSNLKVANYSNSGRFKKRFMYPVGYGLPAFIVAVSAIAGHKNYGTHNHCWLSLHRGFIWSFLGPAAAIILINLVFYFLIIWILRSKLSSLNKEVSTLQDTKVMTFKAIVQLFVLGCSWGIGLFIFIEVGKTVRLIVAYLFTIINVLQGVLIFMVHCLLNRQVRMEYKKWFHRLRKEVESESTEVSHSTTHTKMGLSLNLENFCPTGNLHDPSDSILPSTEVAGVYLSTPRSHMGAEDVNSGTHAYWSRTISD
Tissue specificity:Predominantly expressed in myeloid cells. Predominantly expressed on resident macrophages. {ECO:0000269|PubMed:11564768, ECO:0000269|PubMed:12023293}.
Induction:Up-regulated following macrophage activation. {ECO:0000269|PubMed:12023293}.
Developmental stage:
Protein families:G-protein coupled receptor 2 family, Adhesion G-protein coupled receptor (ADGR) subfamily