UFL1_MOUSE Q8CCJ3
We list detailed information on various proteins on this webpage, which EnkiLife references when developing protein-related products. The protein data is sourced from UniProt, and since UniProt updates its information periodically, the data on our webpage may not always be up-to-date or may contain inaccuracies. If you notice any errors while browsing, we warmly welcome your feedback. Additionally, if you have any suggestions regarding any aspect of our website, please feel free to share them with us. As a token of our appreciation, we will offer a free product or a discount voucher for purchases to scientists who provide feedback. Please contact us at Email: order@enkilife.com; to share your feedback and get your rewards.
UniProt:Q8CCJ3
Recommended name：E3 UFM1-protein ligase 1
EC number：EC 2.3.2.-
Alternative names：(E3 UFM1-protein transferase 1) (Multiple alpha-helix protein located at ER) (Regulator of C53/LZAP and DDRGK1)
Cleaved into：
GeneID：67490
Gene names (primary )：Ufl1
Gene names (synonym )：Kiaa0776 Maxer Rcad
Gene names (ORF )：
Length：793
Mass：89520
Sequence：MADAWEEIRRLAADFQRAQFAESTQRLSERNCIEIVNKLISQKQLEVVHTLDGKEYITPAQISKEMRDELHVRGGRVNIVDLQQVINVDLTHIESRVSDIIKSEKHVQMVLGQLIDENYLDQLSEEVNDKLQESGQVTVSELCKAYDLPGDFLTQALTQRLGRIINGHLDLDNRGVIFTEAFVARHKARIRGLFSAITRPTPVNSLVSKYGFQEQLLYSVLEDLVSTGRLRGTVVGGRQDKAVFVPDIYSRTQSTWVDSFFRQNGYLEFDALSRLGIPDAVNYIKKRYKNTQLLFLKATCVGQGLVDQVEASVEEAISSGTWVDISPLLPSSLSVEDAAMLLQQVMRPFGKLASAIVFSDTVVVSEKFITDCTGLFSERMHQKAEKEMKNNPVHLITEEDLKQISILESVNTSKKDKKDERRKKATEGSGSVRGGGGGNAREYKIKKTKKKGRKDEDSDDESQSSHGGKKKPDITFMFQDEIEDCLRKHIQDAPEEFISELAEYLIKPLNKMYLEVVRSVFMSSTSASGTGRKRTIKDLQEEVSNLYNNIRLFEKGMKYFADDTQTALTKHLLKTVCTDITNLMFNFLASDFLMAVEEPAAITSDIRKKILSKLTEETKVALTKLHNSLNEKSIEDFLSCLDSATEACDIMVKKGDKKRERQILFQHRQALCEQLKVTEDPALILHLTAVLLFQLSTHSMLHAPGRCVPQIIAFLHSKIPEDQHTLLVKYQGLVVKQLVSQNKKTGQGEDPSSDELDKEQHDVTNATRKELQELSLSIKDLVLKSRKSSVTEE
Tissue specificity：Ubiquitously expressed with higher expression in pancreatic islets and other secretory tissues (PubMed:20228063, PubMed:21494687). In the embryonic brain at E17, detected in Sox2-positive neural stem cells and in Slc1a3/GLAST-positive radial glia (PubMed:20531390). In perinatal brain, highly expressed in Slc1a3-positive Bergmann glia of the cerebellum (PubMed:20531390). Continues to be expressed in Bergmann glia of adult brain at 16 weeks (PubMed:20531390). Expressed in adult heart (PubMed:30354401). Highly expressed in the intestinal exocrine cells (PubMed:30701081). {ECO:0000269|PubMed:20228063, ECO:0000269|PubMed:20531390, ECO:0000269|PubMed:21494687, ECO:0000269|PubMed:30354401, ECO:0000269|PubMed:30701081}.
Induction：Up-regulated in hypertrophic hearts (at protein level). {ECO:0000269|PubMed:30354401}.
Developmental stage：
Protein families：UFL1 family