TRPV6_MOUSE Q91WD2
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UniProt:Q91WD2
Recommended name：Transient receptor potential cation channel subfamily V member 6
EC number：
Alternative names：(TrpV6) (Calcium transport protein 1) (CaT1) (Epithelial calcium channel 2) (ECaC2)
Cleaved into：
GeneID：64177
Gene names (primary )：Trpv6
Gene names (synonym )：
Gene names (ORF )：
Length：767
Mass：87387
Sequence：MGPLQREDRPALGGANVAPGSSPVGVWHQPQPPKEPAFHPMGWSLPKEKGLILCLWNKFCRWFHRQESWAQSRDEQNLLQQKRIWESPLLLAAKENDVQALSKLLKFEGCEVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQKRKHIQWTYGPLTSTLYDLTEIDSSGDDQSLLELIVTTKKREARQILDQTPVKELVSLKWKRYGRPYFCVLGAIYVLYIICFTMCCVYRPLKPRITNRTNPRDNTLMQQKLLQEAYVTPKDDLRLVGELVSIVGAVIILLVEIPDIFRLGVTRFFGQTILGGPFHVIIITYAFMVLVTMVMRLTNVDGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPDELGHFYDYPMALFSTFELFLTIIDGPANYDVDLPFMYSVTYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQVVATTVMLERKLPRCLWPRSGICGREYGLGDRWFLRVEDRQDLNRQRIRRYAQAFQQQDGLYSEDLEKDSGEKLETARPFGAYLSFPTPSVSRSTSRSSTNWERLRQGALRKDLRGIINRGLEDGEGWEYQI
Tissue specificity：Detected in intestine (at protein level) (PubMed:17129178). Abundantly expressed in pancreas and placenta, and to a much lesser extent in stomach and kidney (PubMed:12765696). Detected in kidney and duodenum (PubMed:17129178, PubMed:20399919). {ECO:0000269|PubMed:12765696, ECO:0000269|PubMed:17129178, ECO:0000269|PubMed:20399919}.
Induction：Up-regulated in intestine by exposure to a low-calcium diet (PubMed:17129178, PubMed:22878123). Down-regulated in intestine in response to a high-calcium diet (PubMed:17129178). {ECO:0000269|PubMed:17129178, ECO:0000269|PubMed:22878123}.
Developmental stage：
Protein families：Transient receptor (TC 1.A.4) family, TrpV subfamily, TRPV6 sub-subfamily