EST1_MOUSE Q8VCC2
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UniProt:Q8VCC2
Recommended name：Liver carboxylesterase 1
EC number：EC 3.1.1.1
Alternative names：(Acyl-coenzyme A:cholesterol acyltransferase) (Carboxylesterase 1G) (Cholesteryl ester hydrolase) (CEH) (ES-x)
Cleaved into：
GeneID：12623
Gene names (primary )：Ces1
Gene names (synonym )：Ces1g
Gene names (ORF )：
Length：565
Mass：62680
Sequence：MWLCALSLISLTACLSLGHPSLPPVVHTVHGKVLGKYVTLEGFSQPVAVFLGVPFAKPPLGSLRFAPPEPAEPWSFVKHTTSYPPLCYQNPEAALRLAELFTNQRKIIPHKFSEDCLYLNIYTPADLTQNSRLPVMVWIHGGGLVIDGASTYDGVPLAVHENVVVVVIQYRLGIWGFFSTEDEHSRGNWGHLDQVAALHWVQDNIANFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAIAQSSVIFNPCLFGRAARPLAKKIAALAGCKTTTSAAMVHCLRQKTEDELLEVSLKMKFGTVDFLGDPRESYPFLPTVIDGVLLPKAPEEILAEKSFNTVPYMVGINKHEFGWIIPMFLDFPLSERKLDQKTAASILWQAYPILNISEKLIPAAIEKYLGGTEDPATMTDLFLDLIGDIMFGVPSVIVSRSHRDAGAPTYMYEYQYRPSFVSDDRPQELLGDHADELFSVWGAPFLKEGASEEEINLSKMVMKFWANFARNGNPNGEGLPHWPEYDQKEGYLQIGVPAQAAHRLKDKEVDFWTELRAKETAERSSHREHVEL
Tissue specificity：Detected in kidney, liver and lung. {ECO:0000269|PubMed:9565681}.
Induction：Up-regulated in liver upon feeding a diet enriched in cholestyramine or cholate. {ECO:0000269|PubMed:9565681}.
Developmental stage：
Protein families：Type-B carboxylesterase/lipase family