DERL2_MOUSE Q8BNI4
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UniProt:Q8BNI4
Recommended name:Derlin-2
EC number:
Alternative names:(Degradation in endoplasmic reticulum protein 2) (Der1-like protein 2) (F-LANa)
Cleaved into:
GeneID:116891
Gene names (primary ):Derl2
Gene names (synonym ):Der2 Flana
Gene names (ORF ):
Length:239
Mass:27640
Sequence:MAYQSLRLEYLQIPPVSRAYTTACVLTTAAVQLELITPFQLYFNPELIFKHFQIWRLITNFLFFGPVGFNFLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLFGLFVSLVFLGQAFTIMLVYVWSRRNPYVRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIAVGHIYFFLEDIFPNQPGGIRILKTPSILRTIFDTPDEDPNYNPLPEERPGGFAWGEGQRLGG
Tissue specificity:Widely expressed, with lowest levels in brain and heart. {ECO:0000269|PubMed:11500051, ECO:0000269|PubMed:16186509}.
Induction:Up-regulated in response to endoplasmic reticulum stress via the ERN1-XBP1 pathway of the unfolded protein response (UPR). {ECO:0000269|PubMed:16186509, ECO:0000269|PubMed:16449189}.
Developmental stage:
Protein families:Derlin family